Substituted thienyl and furyl acylguanidines and methods of their use as beta-secretase modulators
The present invention provides a substituted thienyl or furyl acylguanidine compound of formula I The present invention also provides methods for the inhibition of β-secretase (BACE) and for the treatment of β-amyloid deposits and neurofibrillary tangles.
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(2008/06/13)
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