- Iron-Catalyzed Cross-Coupling of Functionalized Benzylmanganese Halides with Alkenyl Iodides, Bromides, and Triflates
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Various substituted benzylic manganese chlorides were prepared by insertion of magnesium turnings in the presence of MnCl2·2LiCl in THF at -5 °C within 2 h. These benzylic manganese reagents underwent smooth cross-couplings with various functionalized alkenyl iodides, bromides, and triflates or iodoacrylates in the presence of 10 mol % FeCl2 at 25 °C for 1-12 h. Mechanistic studies showed that benzylic manganese halides produced, in the presence of FeCl2, a very reactive iron ate complex.
- Desaintjean, Alexandre,Belrhomari, Sophia,Rousseau, Lidie,Lefèvre, Guillaume,Knochel, Paul
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supporting information
p. 8684 - 8688
(2019/11/03)
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- Pd-Catalyzed Difluoromethylation of Vinyl Bromides, Triflates, Tosylates, and Nonaflates
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Pd-catalyzed difluoromethylation of di-, tri- or tetra-substituted vinyl bromides, triflates, tosylates and nonaflates under mild conditions is described. The reaction tolerates a wide range of functional groups, such as bromide, chloride, fluoride, ester, amine, nitrile, and protected carbonyl, thus providing a general route for the preparation of difluoromethylated alkenes. Vinyl fantasy: Pd-catalyzed difluoromethylation of di-, tri-, or tetra-substituted vinyl bromides, triflates, tosylates, and nonaflates under mild conditions is described. The reaction tolerates a wide range of functional groups, such as bromide, chloride, fluoride, ester, amine, nitrile, and protected carbonyl, thus providing a general route for the preparation of difluoromethylated alkenes.
- Chang, Dalu,Gu, Yang,Shen, Qilong
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supporting information
p. 6074 - 6078
(2015/04/14)
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- The palladium-catalyzed trifluoromethylation of vinyl sulfonates
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A method for the palladium-catalyzed trifluoromethylation of cyclohexenyl sulfonates has been developed. Various cyclohexenyl triflates and nonaflates underwent trifluoromethylation under mild reaction conditions using a catalyst system composed of Pd(dba
- Cho, Eun Jin,Buchwald, Stephen L.
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supporting information; experimental part
p. 6552 - 6555
(2012/01/15)
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- Iron-catalyzed cross-coupling between alkenyl and dienyl sulfonates and functionalized arylcopper reagents
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Functionalized arylcopper reagents react readily with alkenyl sulfonates in the presence of catalytic amounts of Fe(acac)3, (10 mol%) providing the expected cross-coupling products in good yields. Ester or cyano group are tolerated. This cross-coupling can be performed with dienyl sulfonates leading to the corresponding substituted dienes. Georg Thieme Verlag Stuttgart.
- Dunet, Guillaume,Knochel, Paul
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p. 407 - 410
(2007/10/03)
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