Low pressure vinylation of aryl and vinyl halides via Heck-Mizoroki reactions using ethylene
Aryl bromides and iodides in the presence of catalytic amounts of a palladacycle derived from acetophenone oxime and 2 equiv of potassium acetate react with ethylene under ambient pressure (15-30 psi) to give the corresponding vinylarenes. The reactions work with both electron-deficient and electron-rich aryl compounds and tolerate wide variety of common functional groups. Vinyl bromides lead to 1,3-dienes in moderate yields.
Smith, Craig R.,RajanBabu
supporting information; experimental part
p. 1102 - 1110
(2010/03/25)
Copper(I)-catalyzed intramolecular cyclization reaction of 2-(2'- chlorophenyl)ethanol to give 2,3-dihydrobenzofuran
Functionalized 2,3-dihydrobenzofuran can be synthesized in good yield via an intramolecular cyclization of an aryl chloride and a primary alcohol under the catalysis of copper(I) chloride salt. (C) 2000 Elsevier Science Ltd.
Zhu, Jingyang,Price, Benjamin A.,Zhao, Shannon X.,Skonezny, Paul M.
p. 4011 - 4014
(2007/10/03)
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