A new methodology for the synthesis of β-amino acids
A differentially functionalized succinic acid unit 6 undergoes alkylation with excellent regio- and high stereocontrol at the carbon α to the imide to furnish the alkylated product 7 in 60-83% yield. Selective removal of the imide provides 8 in 80-90% yie
Sibi, Mukund P.,Deshpande, Prasad K.
p. 1461 - 1466
(2007/10/03)
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