- Biotransformation of hydrocortisone by a natural isolate of Nostoc muscorum
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Hydrocortisone was converted in the culture of an isolated strain of the cyanobacterium Nostoc muscorum PTCC 1636 into some androstane and pregnane derivatives. The microorganism was isolated during a screening program from soil samples collected from paddy fields of north of Iran. The bioproducts obtained were purified using chromatographic methods and identified as 11β-hydroxytestosterone, 11β-hydroxyandrost-4-en-3,17-dione and 11β,17α,20β,21-tetrahydroxypregn-4-en-3-one on the basis of their spectroscopic features.
- Yazdi, Mojtaba Tabatabaei,Arabi, Homeira,Faramarzi, Mohammad Ali,Ghasemi, Younes,Amini, Mohsen,Shokravi, Shadman,Mohseni, Farzaneh Aziz
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p. 2205 - 2209
(2007/10/03)
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