O-Methyl Phytocannabinoids: Semi-synthesis, Analysis in Cannabis Flowerheads, and Biological Activity
A general protocol for the selective mono-O-methylation of resorcinyl phytocannabinoids was developed. The availability of semisynthetic monomethyl analogues of cannabigerol, cannabidiol, and cannabidivarin (1a-3a, respectively) made it possible to quanti
Base-catalysed Double-bond Isomerizations of Cannabinoids: Structural and Stereochemical Aspects
Base-catalysed double-bond isomerization offers a convenient, high-yield route to a variety of new cannabinoids, as well as to compounds of this group which are accessible with some difficulty.By this route we have obtained optically active Δ2-