- Chemical constituents of Psychotria nemorosa gardner and antinociceptive activity
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Through dereplication strategies using gas chromatography-mass spectrometry (GC-MS) and ultra fast liquid chromatography-tandem mass spectrometry (UFLC-MS/MS), the ethanol extract from Psycotria nemorosa leaves (Rubiaceae) showed to be composed of: cinnamic acid, dihydroactinidiolide, 4-hydroxy-β-ionone, phytol, isophytol, 4,8,12,16-tetramethylheptadecan- 4-olide, lupeol, a mixture of α/β-amyrin, the keto and acetylated derivatives, besides stigmast- 4-en-3-one, campesterol, stigmasterol and γ-sitosterol by GC-MS. Likewise, by UFLC-MS/MS, the main compounds identified were: butin, resveratrol, rutin, kaempferol 7-O-β-D-glucopyranoside, deacetylasperuloside, epiloganin, hordenine, strictosidine, N-methyl-1,2,3,4-tetrahydro-β-carboline and N-formyl-tryptamine. The antinociceptive activity of the crude extract ant its fractions was reported.
- Calixto, Nivea O.,Cordeiro, Millena S.,Giorno, Thais B. S.,Oliveira, Gibson G.,Lopes, Norberto P.,Fernandes, Patricia D.,Pinto, Angelo C.,Rezende, Claudia M.
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p. 707 - 723
(2017/03/31)
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- Biomimetic oxidation of 3β-hydroxy-olean-12-ene and its acetoxy derivative with monooxygen donors catalyzed by 5,10,15,20-tetraarylporphyrinatoiron(III) chlorides in dichloromethane
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The oxidation of 3β-hydroxy-olean-12-ene with monooxygen donors catalyzed by 5,10,15,20-tetraarylporphyrinatoiron(III) chlorides in dichloromethane gives 3β,11α-dihydroxy-olean-12-ene, 3-oxo-olean-12-ene, 3,11-dioxo-olean-12-ene and 3β-hydroxy-olean-9(11),12-diene whereas the oxidation of 3β-acetoxy-olean-12-ene under similar conditions gives 11(-hydroxy-3β-acetoxy-olean-12-ene, 11-oxo-3β-acetoxy-olean-12-ene and 3β-acetoxy-olean-9(11),12-diene in moderate yields.
- Chauhan,Mohapatra,Mamta,Parkash,Azam
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p. 183 - 189
(2007/10/03)
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- Functionalisation of Saturated Hydrocarbons. Part 6. Selective Oxidation of Steroids and Related Compounds
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The oxidation of a series of steroids by the Gif system gives, almost without exception, the 20-ketone as major isolated product.The side-chain cleavage is made more selective by modification of rings A or B.The oxidation of oleana-1,12-diene-3,11-dione has also been studied and the two principal products have been identified.
- Barton, Derek H. R.,Boivin, Jean,Hill, Christopher H.
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p. 1797 - 1804
(2007/10/02)
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