Hydride adducts of dinitroquinolines in multicomponent Mannich reaction
Dinitro derivatives of 8-oxyquinoline, 8-oxyquinaldine, and 3,4-dihydroquinolin-2-one when reacted with NaBH4 form hydride σH-adducts that are involved into a multicomponent Mannich reaction affording pyridoazabicyclo[3.3.1]nonane.
Medvedeva, A. Yu.,Yakunina,Atroshchenko, Yu. M.,Shumskii,Blokhin
Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. Part 1
6-Nitroquipazine has been known as one of the most potent and selective inhibitors of serotonin transporter in vitro and in vivo. Nine derivatives of 6-nitroquipazine were synthesized and tested for their potential abilities to displace [3H]citalopram binding to the rat cortical membranes. (C) 2000 Elsevier Science Ltd. All rights reserved.