- Ru(ii)-catalyzed allenylation and sequential annulation of: N -tosylbenzamides with propargyl alcohols
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We hereby report Ru(ii)-catalyzed C(sp2)-H allenylation of N-tosylbenzamides to access multi-substituted allenylamides. Furthermore, the allenylamides were converted to the corresponding isoquinolone derivatives via base mediated annulation. The current protocol features low catalyst loading, mild reaction conditions, high functional group compatibility and desired scalability. The unique functionality of the afforded allenes allowed further transformations to expand the practicality of the protocol. This journal is
- Kumar, Shreemoyee,Nair, Akshay M.,Volla, Chandra M. R.
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p. 6280 - 6283
(2021/07/02)
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- Synthesis of uniformly 13C-labeled polycyclic aromatic hydrocarbons
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Convergent synthetic pathways were devised for efficient synthesis of a series of uniformly 13C labeled polycyclic aromatic hydrocarbons de novo from U-13C-benzene and other simple commercially-available 13C-starting compounds. All target products were obtained in excellent yields, including the alternant PAH U-13C-naphthalene, U-13C-phenanthrene, U-13C-anthracene, U- 13C-benz[a]anthracene, U-13C-pyrene and the nonalternant PAH U-13C-fluoranthene.
- Zhang, Zhenfa,Sangaiah, Ramiah,Gold, Avram,Ball, Louise M.
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p. 5431 - 5435
(2011/09/14)
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