The present invention discloses a series of tricyclic compounds and use thereof in preparing a medicament for treating a disease related to CRBN protein. Specifically, the present invention discloses a derivative compound of formula (1) or a pharmaceutically acceptable salt thereof.
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(2021/07/17)
Open-cyclic warfarin isomerism: 5-hydroxywarfarin
Addition of a 5-hydroxy substituent to warfarin shifts the solution equilibrium in chloroform to favor the open isomeric form over the two cyclic diastereomeric hemiketals.X-ray diffraction analysis reveals 5-hy
Castleberry, Brian,Valente, Edward J.,Eggleston, Drake S.
p. 583 - 593
(2007/10/02)
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