The present invention provides compounds having Formula I and their use for the treatment of cancer.
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Page/Page column 9
(2008/06/13)
Benzimidazole C-2 heterocycles as kinase inhibitors
Benzimidazole derivatives having the general formula I are provided. These compounds are useful as tyrosine kinase inhibitors, especially for the treatment of cancer.
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Page/Page column 12
(2010/02/11)
NOVEL TYROSINE KINASE INHIBITORS
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof. The formula (I) compounds inhibit tyrosine kinase enzymes thereby making them useful as anti-cancer agents.
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Page 33
(2008/06/13)
Novel tyrosine kinase inhibitors
The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase enzymes thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases which can be treated by inhibiting tyrosine kinase enzymes.
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Page 20
(2010/11/30)
A novel methodology for preparing 5-chloro- and 5-bromotryptamines and tryptophans, and its application to the synthesis of (±)-bromochelonin B
A novel methodology for introducing chlorine or bromine into the 5- position of tryptamines was found through 1-hydroxytryptamines. The chemistry was applied to the syntheses of (±)-5-chloro-, -5-bromotryptophan derivatives, and (±)-bromochelonin B.
Halogenated 4'-methoxyacetophenones as microbicides and preservatives
Halogenated 4'-methoxyacetophenones of formula I: STR1 wherein X is a halogen; Y is a halogen; and n is 1 or 2 as microbicides for inhibiting the growth of microorganisms in aqueous systems and on surfaces, as well as for inhibiting slime formation in aqueous systems and biocidal compositions containing effective amounts of the halogenated 4'-methoxyacetophenones.
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(2008/06/13)
IMIDAZOLE DERIVATIVES. XXVII. SYNTHESIS AND RADIOPROTECTIVE ACTIVITY OF SUBSTITUTED PHENACYLTHIOIMIDAZOLINE AND 3-PHENYL-5,6-DIHYDROIMIDAZOTHIAZOLE HYDROCHLORIDES
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Iradyan, M. A.,Aroyan, R. A.,Engoyan, A. P.,Grigoryan, G. Kh.,Nersesyan, S. E.,Panosyan, A. G.
p. 455 - 458
(2007/10/02)
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