Novel and efficient synthesis of 7-trifluoromethyl-substituted pyrazolo[1,5-a] pyrimidines with potent antitumor agents
The synthesis of 7-trifluoromethyl-substituted pyrazolo(1,5-a) pyrimidines with potent antitumor agents was investigated. The trifluoromethyl-β- diketones were treated with 5-amino pyrazole carboxylates under microwave condition, using acetic acid as a so