Synthesis of orotidine by intramolecular nucleosidation
An intramolecular nucleosidation approach provides easy access to orotidine in high yields. Notably, orotate itself is used as a leaving group at the anomeric position. This method has the potential for facile access to derivatives of orotidine of therapeutic interest, with implications for prebiotic formation of nucleosides. This journal is
Kim,Krishnamurthy
supporting information
p. 5618 - 5621
(2015/03/30)
Preparation of orotidine, 2' deoxyorotidine, and related compounds