Stereoelectronic Control of the Base-catalysed Rearrangement of 2-Hydroxy-3-oxocarboxylates
The stereochemistry of the alkyl-catalysed rearrangement of α-acetohydroxybutyrate (2-ethyl-2-hydroxy-3-oxobutanoate) was studied.The rearrangement was found to proceed via a transition state in which a syn arrangement of the C-O bonds is preferred over the anti arrangement by a factor of >/= 2:1.
Crout, David H. G.,Lee, Edward R.,Pearson, David P. J.
p. 381 - 385
(2007/10/02)
More Articles about upstream products of 3142-65-2