A concise synthesis of 2-alkenyl-3-phenyl-4H-chromen-4-ones via novel C-C bond formation using sulfone as potential intermediate
A new methodology has been designed for the synthesis of some non-natural 2-alkenyl-3-phenyl-4H-chromen-4-ones of potential biological importance. The strategy makes use of appropriately substituted heteroaryl sulfone as the potent intermediate. An ambide
Khanna, Leena,Khanna, Pankaj,Jain, Subhash C.
p. 945 - 954
(2019/05/21)
COMPOUNDS USEFUL FOR THE INHIBITION OF ALDH
The present invention provides novel antidipsotropic compounds. The invention further provides methods of inhibiting ALDH-2 using the compounds described herein. Methods for modulating alcohol consumption, alcohol dependence and/or alcohol abuse by administering the compounds of the invention to an individual are also provided. The present invention further provides a rationale for designing additional novel antidipsotropic compounds.
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Page/Page column 17
(2010/11/30)
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