- REDUCTION SENSITIVE BIODEGRADABLE POLYESTERAMIDES
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The present invention relates to biodegradable polyesteramides (PEAs) comprising hydrophobic alpha -amino acids, diols, aliphatic dicarboxylic acids and optionally diamines whereby at least one of the dicarboxylic acids, diols or diamines comprises disulp
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Page/Page column 14
(2016/04/19)
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- Bioerodable poly(etheresteramides) and medical article uses
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Bioerodable poly(etheresteramides) and matrices formed therefrom, such as medical device coatings, are described. The matrices show desirable erosion properties desirable for therapeutic use. The matrices can include a bioactive agent which can be used to
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Page/Page column 21-22
(2016/08/03)
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- From macro to micro to nano: The development of a novel lysine based hydrogel platform and enzyme triggered self-assembly of macro hydrogel into nanogel
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A novel L-lysine based multifunctional crosslinker family was developed and utilized to fabricate a 100% pure poly(ester amide) (PEA) hydrogel with unique structure via a novel gelation strategy in a single and rapid step. Enzyme triggered biodegradation
- Wu, De-Qun,Wu, Jun,Qin, Xiao-Hong,Chu, Chih-Chang
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p. 2286 - 2294
(2015/03/18)
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- CATIONIC MATERIALS AND FORMULATIONS FOR DRUG DELIVERY
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Cationic polymers are provided for delivering anionic active agents, preferably in the form or nanoparticles and other nanostructures. The polymer can be a polycation homopolymer or a copolymer containing a polycation block. The polycations and polycation
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Page/Page column 61
(2015/07/15)
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- Water insoluble cationic poly(ester amide)s: Synthesis, characterization and applications
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We reported a new family of water insoluble, biocompatible and biodegradable cationic arginine and phenylalanine based poly(ester amide)s (Arg-Phe-PEAs) for potential biomedical applications. The Arg-Phe-PEA consists of 3 building blocks: amino acids, dio
- Wu, Jun,Chu, Chih-Chang
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p. 353 - 360
(2013/06/26)
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- Implantable medical devices comprising semi-crystalline poly(easter-amide)
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The current invention relates to an implantable medical device made of semi-crystalline poly(ester amide) (PEA) polymer.
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Page/Page column 8
(2010/11/29)
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- BIODEGRADABLE WATER SOLUBLE POLYMERS
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The invention provides biodegradable, water soluble PEA, PEUR and PEU carrier polymers, which can be used to conjugate, and thereby stabilize and/or solublize, bioactive agents via polar uncharged or charged groups and activated ester or amino groups cont
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Page/Page column 46
(2010/11/29)
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- A new homobifunctional p-nitro phenyl ester coupling reagent for the preparation of neoglycoproteins
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(Chemical equation presented) A new linker system has been designed and applied to neoglycoprotein synthesis. Reaction of oligosaccharide ω-aminoalkyl glycosides with homobifunctional adipic acid p-nitrophenyl diesters in dry DMF gave the corresponding am
- Wu, Xiangyang,Ling, Chang-Chun,Bundle, David R.
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p. 4407 - 4410
(2007/10/03)
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- Activated polycondensation in synthesis of polyamidobenzimidazoles
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Formation of polyaminoimides by activated copolycondensation of bis-p-nitrophenyl esters of aliphatic and aromatic dicarboxylic acids with aromatic tetraamines and ε-caprolactam in N-methylpyrrolidone was studied. The optimal synthesis conditions were det
- Mognonov,Mazurevskaya,Ul'zetueva,Izyneev
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p. 1066 - 1069
(2007/10/03)
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