- Bipyridinium chloride supported rice husk silica: An efficient nanocomposite for the one-pot preparation of spirooxindole pyran and 2-amino-4h-chromene derivatives
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In this paper, rice-husk-silica supported n-propyl bipyridinium chloride (RHPrBPCl) has been prepared as a heterogeneous catalyst. RHPrBPCl has been successfully applied in the one-pot preparation of spirooxindole pyran and 2-amino- 4H-chromene derivative
- KIASAT, Ali Reza,HAMID, Sheida,SAGHANEZHAD, Seyyed Jafar
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p. 927 - 934
(2021/02/05)
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- One-pot Synthesis of 2-Amino-4H-Chromenes using Chicken Eggshell Waste as Green Catalyst under Solvent-Free Conditions
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Chicken eggshell waste has been employed as green and efficient catalyst for the preparation of 2-amino-4H-chromenes. The aromatic aldehydes were condensed with malononitrile and 1-naphthol or 2-naphthol under solvent-free condition in the presence of chi
- Gadhave, Anil,Uphade, Bhagwat
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p. 387 - 394
(2021/01/25)
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- Bipyridinium chloride supported rice husk silica: An efficient nanocomposite for the one-pot preparation of spirooxindole pyran and 2-amino-4H-chromene derivatives
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In this paper, rice-husk-silica supported n-propyl bipyridinium chloride (RHPrBPCl) has been prepared as a heterogeneous catalyst. RHPrBPCl has been successfully applied in the one-pot preparation of spirooxindole pyran and 2-amino-4H-chromene derivatives
- Hamid, Sheida,Kiasat, Ali Reza,Saghanezhad, Seyyed Jafar
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p. 927 - 934
(2020/06/27)
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- Triethanolamine-catalyzed expeditious and greener synthesis of 2-amino-4H-chromenes
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Triethanolamine (TEOA), an inexpensive and eco-friendly base, was used to efficiently catalyze the three-component condensation reaction of heterocyclic/aromatic aldehyde, (α/β)-naphthol, and malononitrile in water to give the corresponding substituted 2-
- Patel, Anilkumar S.,Tala, Satishkumar D.,Nariya, Pankajkumar B.,Ladva, Kartik D.,Kapuriya, Naval P.
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p. 247 - 252
(2018/10/31)
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- Ni–Al2O3 as reusable heterogeneous catalyst for expedient one-pot synthesis of naphthopyrans
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Abstract: Ni–Al2O3 is an efficient and reusable heterogeneous catalyst for the synthesis of naphthopyrans by one-pot three-component reaction of naphthols, aldehydes, and malononitrile in EtOH/H2O (1:1) solvent medium. A c
- Kalita, Subarna Jyoti,Saikia, Nilakhy,Deka, Dibakar Chandra,Mecadon, Hormi
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p. 6863 - 6871
(2016/08/25)
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- Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Aβ1?42Aggregation Inhibitors for Alzheimer's Disease Therapy
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Given the complex nature of Alzheimer′s disease (AD), compounds that are able to simultaneously address two or more AD-associated targets show greater promise for development into drugs for AD therapy. Herein we report an efficient two-step synthesis and biological evaluation of new racemic benzochromene derivatives as antioxidants, inhibitors of cholinesterase and β-amyloid (Aβ1?42) aggregation. Based on the results of the primary screening, we identified 15-(3-methoxyphenyl)-9,11,12,15-tetrahydro-10H,14H-benzo[5,6]chromeno[2,3-d]pyrido[1,2-a]pyrimidin-14-imine (3 e) and 16-(3-methoxyphenyl)-9,10,11,12,13,16-hexahydro-15H-benzo[5′,6′]chromeno[2′,3′:4,5]pyrimido[1,2-a]azepin-15-imine (3 f) as new potential multitarget-directed ligands for AD therapy. Further in-depth biological analysis showed that compound 3 f is a good human acetylcholinesterase inhibitor [IC50=(0.36±0.02) μm], has strong antioxidant activity (3.61 μmol Trolox equivalents), and moderate Aβ1?42antiaggregating power (40.3 %).
- Dgachi, Youssef,Ismaili, Lhassane,Knez, Damijan,Benchekroun, Mohamed,Martin, Hélène,Sza?aj, Natalia,Wehle, Sarah,Bautista-Aguilera, Oscar M.,Luzet, Vincent,Bonnet, Alexandre,Malawska, Barbara,Gobec, Stanislav,Chioua, Mourad,Decker, Michael,Chabchoub, Fakher,Marco-Contelles, José
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p. 1318 - 1327
(2016/07/21)
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- Straightforward and solvent-free synthesis of 2-amino-4H-chromenes in the presence of a choline-based magnetic ionic liquid as catalyst
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Choline tetrachloroferrate with a magnetic response property is applied in multicomponent one-pot synthesis of 2-amino-4H-chromenes as effective catalyst. The catalyst is characterized by the UV–Vis and Raman spectroscopies and by the electrospray ionizat
- Khodajoo,Sayyahi,Saghanezhad
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p. 1177 - 1181
(2016/07/06)
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- Nano silica-bonded aminoethylpiperazine: A highly efficient and reusable heterogeneous catalyst for the synthesis of 4H-chromene and 12H-chromeno[2,3-d]pyrimidine derivatives
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Abstract The reaction of nano silica with 3-chloropropyltrimethoxysilane followed by treatment with aminoethylpiperazine afforded nano silica-bonded aminoethylpiperazine (SB-APP). The structure of the synthesized SB-APP was characterized by FT-IR, TGA, BE
- Tajbakhsh, Mahmood,Kariminasab, Mohaddeseh,Alinezhad, Heshmatollah,Hosseinzadeh, Rahman,Rezaee, Parizad,Tajbakhsh, Mahgol,Gazvini, Helia Janatian,Amiri, Mohammadreza Azizi
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p. 1405 - 1414
(2015/06/22)
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- An efficient green synthesis of 3-amino-1H-chromenes catalyzed by ZnO nanoparticles thin-film
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A very simple and environmentally benign approach for the synthesis of 3-amino-1H-chromenes is described using ZnO nanoparticles thin-film as an efficient heterogeneous catalyst in green media, namely water. The mild reaction conditions, reusability of th
- Abdolmohammadi, Shahrzad,Afsharpour, Maryam,Keshavarz-Fatideh, Shima
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p. 203 - 210
(2015/02/18)
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- Silica-supported yttrium nitrate hexahydrate as a heterogeneous catalyst for the synthesis of 2-Amino-4H-chromenes in water
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Silica-supported yttrium nitrate hexahydrate (Y(NO3)3.6H2O/SiO2) has been found to be an efficient and reusable catalyst for the synthesis of 2-amino-4H-chromenes via a one-pot aqueous three-component reaction b
- Karami, Bahador,Farahi, Mahnaz,Bazrafshan, Masoomeh,Khodabakhshi, Saeed
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p. 109 - 112
(2014/12/10)
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- On water CuSO4. 5H2O-catalyzed synthesis of 2-amino-4H-chromenes
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Sustainable development is a balance between environment and development. Sustainable development requires sustainable supplies of clean, affordable, and renewable energy sources that do not cause negative impact to the society. This article introduces a
- Behbahani, Farahnaz Kargar,Maryam, Sadeghi
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p. 357 - 360
(2013/07/26)
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- L-proline as reusable and organo catalyst for the one-pot synthesis of substituted 2-Amino-4H-chromenes
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L-proline catalyzed one-pot three-component condensation reaction of aromatic aldehydes, malononitrile and naphthols proceeded in EtOH to afford corresponding 2-Amino-4H-chromenes in high to excellent yields at reflux conditions. The protocol found to be
- Behbahani, Farahnaz Kargar,Ghorbani, Mehdi,Sadeghpour, Mahdieh,Mirzaei, Mohamad
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p. 191 - 194
(2013/07/26)
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- An efficient one-pot synthesis of substituted 1h-naphtho[2,1-b]pyrans and 4h-1-benzopyrans (=Chromenes) under solvent-free microwave-irradiation conditions
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A facile heterogeneous synthesis of 3-amino-1-aryl-1H-naphtho[2,1-b]pyran and 2-amino-4-aryl-4H-1-benzopyran derivatives 3 and 5, respectively, was carried out efficiently by one-pot three-component coupling of an aromatic aldehyde 1, an active methylene compound 2, and naphthalen-2-ol or a phenol 4 in the presence of 5-A molecular sieves under solvent-free microwave-irradiation conditions (Scheme 1 and 2, Tables 1 and 2). The catalyst was recovered and recycled (Table 3). Copyright
- Shekhar, Adimulam Chandra,Kumar, Akula Ravi,Sathaiah, Gangaram,Raju, Kengiri,Rao, Pamulaparthy Shanthan,Sridhar, Madabhushi,Narsaiah, Banda,Srinivas, Punnamraju Venkata Satya Surya,Sridhar, Balasubramanian
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experimental part
p. 502 - 508
(2012/05/04)
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