Trimethylaluminium-mediated reaction of primary carboxamides with amines and indoles: A convenient synthesis of amidines and indole-3-acylimines
A simple, convenient and general method, exhibiting good functional group tolerance, is described for the synthesis of N- and N,N-disubstituted amidines by the reaction of primary carboxamides with amines mediated by trimethylaluminium (AlMe3).
Velavan,Sumathi,Balasubramanian
p. 5806 - 5815
(2014/10/16)
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