- Structure and Synthesis of the Aryltetralin Lignans Hypophyllanthin and Nirtetralin
-
Structures previously suggested for hypophyllanthin, the major aryltetralin lignan constituent of Phyllanthus niruri are shown to be incorrect.The structure r-1-(3,4-dimethoxyphenyl)-6-methoxy-t-2,c-3-bismethoxymethyl-7,8-methylenedioxy-1,2,3,4-tetrahydronaphthalene (5) now proposed is confirmed by an unambiguous synthesis.Synthesis of the congener, nirtetralin, is also described.
- Schneiders, Gail E.,Stevenson, Robert
-
p. 999 - 1004
(2007/10/02)
-
- STRUCTURE AND SYNTHESYS OF HYPOPHYLLANTHIN, NIRTETRALIN, PHYLTETRALIN AND LINTETRALIN
-
Structures propounded for the four aryltetralin lignan constituents isolated from Phyllanthus niruri Linn. are confirmed by syntheses of their (+/-)-forms.
- Ganeshpure, Pralhad A.,Schneiders, Gail E,Stevenson, Robert
-
p. 393 - 396
(2007/10/02)
-