- Quinazolone thiazole compounds, and preparation method and application thereof
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The invention relates to quinazolone thiazole compounds, and a preparation method and an application thereof, and belongs to the technical field of chemical synthesis. The quinazolone thiazole compounds are represented by general formula I to IV. The compounds have a certain inhibitory activity to one or more of Gram-positive bacteria, Gram-negative bacteria and fungi, and can be used to prepare antibacterial and/or antifungal drugs in order to provide efficient and safe drug candidate drugs for clinical ant-microbial treatment and contribute to solve clinical treatment problems such as increasing drug resistance, stubborn pathogenic microorganisms and emerging harmful microorganisms.
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Paragraph 0078-0080
(2019/10/23)
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- Phosphorhydrazides as urease and acetylcholinesterase inhibitors: biological evaluation and QSAR study
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New phosphorhydrazide compounds (1–7, 13, 15–16) and thiophosphorhydrazide (14 and 17) were synthesized and characterized by 31P, 13C, 1H NMR and IR spectroscopy. Furthermore, the crystal structure of compound (C6/su
- Asadi, Lida,Gholivand, Khodayar,Zare, Karim
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p. 1213 - 1223
(2016/06/09)
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