- Scalable synthesis of 4-substituted 5-bromo-6-methylpyrimidines
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Small halogenated heteroaromatic ring systems are valuable monomers, which can enable rapid access to novel and desirable chemical space, in part because of their ability to participate in established cross coupling chemistry such as the Heck, Stille, and Suzuki reactions. Described is a practical, scalable synthetic route towards the construction of a diverse array of 4-substituted 5-bromo-6-methylpyrimidine monomers. Georg Thieme Verlag Stuttgart · New York.
- Wang, Zhihan,Chi, Yushi,Harris, Anthony R.,Gray, David,Davoren, Jennifer E.
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p. 1529 - 1531
(2011/06/23)
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