Isolation, structure determination, and synthesis of cyclic tetraglutamic acids from box jellyfish species alatina alata and chironex yamaguchii
Cubozoan nematocyst venoms contain known cytolytic and hemolytic proteins, but small molecule components have not been previously reported from cubozoan venom. We screened nematocyst extracts of Alatina alata and Chironex yamaguchii by LC-MS for the prese
Total Synthesis and Antimicrobial Activity of Chlorocatechelin A
Chlorocatechelin A (1) is a structurally unique microbial siderophore containing two units of 4-chloro-2,3-dihydroxybenzoic acid (CDB) and a characteristic acylguanidine structure. Purification from the microbe culture is not an easy task due to the labil
PROBLEM TO BE SOLVED: To provide a novel compound useful as an aminopeptidase A inhibitor. SOLUTION: This invention provides a compound represented by formula (I) or salt thereof, and a pharmaceutical composition comprising the same, wherein R1
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Paragraph 0074-0075
(2018/02/08)
N-ACYL-gamma-GLUTAMYL IMINO AND AMINO ACIDS AND ESTERS
Compounds of the formula STR1 wherein X is various imino or amino acids or esters are disclosed. These compounds possess angiotensin converting enzyme inhibition activity and depending upon the definition of X also possess enkephalinase inhibition activit
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(2008/06/13)
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