cas 34675-84-8, CETRAXATE, HYDROCHLORIDE | Articles data ｜lookchem

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34675-84-8

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Biocatalytic deprotection of a cetraxate ester by Microbacterium sp. strain 7-1W cells
Enzymatic deprotection of the terminal ester bond of a cetraxate methyl ester was done with resting cells of Microbacterium sp. strain 7-1W, which produces an esterase catalyzing a regioselective hydrolysis reaction, as the catalyst. When 20 g of cetraxate methyl ester in 50 ml of a reaction mixture was incubated with 5 g of wet cells for 17 h, 96% of the substrate was converted to the desired product, cetraxate, quantitatively.
Honda, Kohsuke,Sakamoto, Keiji,Kita, Shinji,Kataoka, Michihiko,Shimizu, Sakayu
p. 192 - 194
(2003)
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Medicinal chemical studies on antiplasmin drugs. 4. Chemical modification of trans-4-aminomethylcyclohexanecarboxylic acid and its effect on antiplasmin activity.
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Okano,Inaoka,Funabashi,Iwamoto,Isoda
p. 247 - 255
(2007/10/05)

More Articles about upstream products of 34675-84-8

Chemical Properties

Melting Point: melts over a range of 200-280°
Boiling Point: 480.9°Cat760mmHg
Flash Point:244.6°C
Density: 1.182g/cm³
Solubility:DMSO (Slightly), Methanol (Slightly)
Storage Temp.:2-8°C
Vapor Pressure: 4.67E-10mmHg at 25°C
Refractive Index: 1.5200 (estimate)
PKA: 4.61±0.10(Predicted)
PSA: 89.62000
LogP: 3.07460

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