- 3-hydroxy-2-butanone-2,4-dinitrophenylhydrazone and method for detecting acetoin content in exhaled breath by using same
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The invention provides 3-hydroxyl-2-butanone-2,4-dinitrophenylhydrazone and a method for detecting acetoin content in exhaled breath by using the 3-hydroxyl-2-butanone-2,4-dinitrophenylhydrazone, andbelongs to the field of biochemical engineering. The inv
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Paragraph 0039-0053
(2020/10/14)
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- Revisiting the reaction of hydroxyl radicals with vicinal diols in water
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The carbonyl products of the reactions of hydroxyl radicals with three vicinal diols (ethane-1,2-diol, propane-1,2-diol and butane-2,3-diol) have been identified and quantified. Hydroxyl radicals were produced by γ-radiolysis of N2O-saturated aqueous solutions. The reactions result in the formation of alkoxyl radicals (~15%) followed by β-fragmentation, and α-hydroxyl alkyl radicals that undergo H2O elimination. The latter process is part of a radical chain reaction at higher diol concentrations.
- Jiang, Dong,Barata-Vallejo, Sebastian,Golding, Bernard T.,Ferreri, Carla,Chatgilialoglu, Chryssostomos
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supporting information; experimental part
p. 1102 - 1107
(2012/04/04)
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- Kinetics and mechanism of the oxidation of diols by butyltriphenylphosphonium dichromate
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The oxidation of four vicinal, four non-vicinal diols and one of their monoethers by butyltriphenylphosphonium dichromate (BTPPD), in dimethylsulfoxide (DMSO), resulted in the formation of corresponding hydroxyaldehyde as a main product of the oxidation. The reactions are of first order with respect to BTPPD, however, second order dependence is obtained with respect to each the diol and hydrogen ion. The oxidation of [1,1,2,2-2H 4]ethanediol exhibited primary kinetic isotope effect (k H/kD = 6.61 at 298 K). The temperature dependence of the kinetic isotope effect suggested the symmetrical transition state in the rate-determining step. The rate constants of oxidation of four vicinal diols show excellent correlation with Taft's ∑ σ* values with negative reaction constant, ρz.ast;. The rate of oxidation of ethanediol has been determined in nineteen different solvents. An analysis of the solvent effect indicates the importance of the cation-solvating power of the solvents. A suitable mechanism has been postulated involving the formation of chromate ester in a pre-equilibrium.
- Panday, Dinesh,Kothari, Seema
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experimental part
p. 918 - 925
(2011/09/19)
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- Oxidation of some vicinal and non-vicinal diols by morpholinium chlorochromate: A kinetic and mechanistic study
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The kinetics of oxidation of four vicinal, four non-vicinal diols and two of their monoethers by morpholinium chlorochromate (MCC) have been studied in dimethylsulphoxide (DMSO). The main product of oxidation is the corresponding hydroxycarbonyl compound. The reaction is first order in MCC and the diols. The reaction is catalysed by hydrogen ions. The hydrogen ion dependence is taking the form : kobs = a + b [H+]. The oxidation of [1,1,2,2-2H4]ethanediol exhibits a substantial primary kinetic isotope effect (kH/kD = 5.82 at 298 K). The reaction has been studied in nineteen different organic solvents and the solvent effect has been analysed using Taft's and Swain's multiparametric equations. The temperature dependence of the kinetic isotope effect indicates the presence of a symmetrical transition state in the rate-determining step. A suitable mechanism has been proposed.
- Barthora,Baghmar,Agarwal,Sharma, Vinita
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experimental part
p. 677 - 683
(2012/04/10)
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- Revealing substrate promiscuity of 1-deoxy-D-xylulose 5-phosphate synthase
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A study of DXP synthase has revealed flexibility In the acceptor substrate binding pocket for nonpolar substrates and has uncovered new details of the catalytic mechanism to show that pyruvate can act as both donor and acceptor substrate.
- Brammer, Leighanne A.,Meyers, Caren Freel
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supporting information; experimental part
p. 4748 - 4751
(2010/02/28)
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