cas 35142-05-3, aristolic acid | Articles data

Articles about 35142-05-3Total 4 be found

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Conversion of aristolochic acid i into aristolic acid by reaction with cysteine and glutathione: Biological implications
Aristolochic acid I (AA-I), naturally occurring in Aristolochia plants, is a potent nephrotoxin and carcinogen. Here we report that AA-I suffers hydrogenolysis with loss of the nitro group by reaction with cysteine or glutathione to give aristolic acid. Since the reaction can proceed in aqueous solutions at pH 7.0 and 37 C, it is inferred that it may also occur in biological systems and contribute to the nephrotoxic effects induced by AA-I.
Priestap, Horacio A.,Barbieri, Manuel A.
p. 965 - 968
(2013)
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Methylendioxyphenathrene and stilben derivatives, process for the preparation thereof, pharmaceutical compositions using these, and therapeutic applications
The present invention provides compounds of the general formula: STR1 wherein R1 is a hydrogen atom or a methoxy or ethoxy radical and R2 and R3 are hydrogen atoms or R2 and R3 together represent an aromatic carbon-carbon bond and R1 is a hydrogen atom, a hydroxyl group or an ethoxy radical; and the pharmaceutically acceptable salts thereof. The present invention also provides processes for the preparation of these compounds and pharmaceutical compositions containing them, as well as their use in therapy.
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(2008/06/13)

Semisynthetic derivatives of aristolchocic acids I and II as reference compounds for metabolites in the rat
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Krumbiegel,Roth
p. 264 - 270
(2007/10/02)

A PHENANTHROID LACTONE, STEROID AND LIGNANS FROM ARISTOLOCHIA INDICA
Aristololide, a new phenanthroid lactone characterized as 1b, has been isolated from the roots of Aristolochia indica Linn., along with 5α-stigmastane-3,6-dione, (-)-cubebin and (-)-hinokinin.
Achari, Basudeb,Bandyopadhyay, Soumitra,Saha, Chitta R.,Pakrashi, Satyesh C.
p. 771 - 774
(2007/10/02)

Chemical Properties

Melting Point: 292°C
Boiling Point: 550.1°C at 760 mmHg
Flash Point:210.3°C
Density: 1.442g/cm³
Vapor Pressure: 6.2E-13mmHg at 25°C
Refractive Index: 1.6200 (estimate)
PSA: 64.99000
LogP: 3.42850

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Chemical Properties

Melting Point: 292°C

Boiling Point: 550.1°C at 760 mmHg

Flash Point:210.3°C

Density: 1.442g/cm³

Vapor Pressure: 6.2E-13mmHg at 25°C

Refractive Index: 1.6200 (estimate)

PSA: 64.99000

LogP: 3.42850

Global suppliers and manufacturers of 35142-05-3total 3 suppliers on LookChem

Article Database

35142-05-3

Articles about 35142-05-3Total 4 be found

More Articles about upstream products of 35142-05-3

More Articles about downstream products of 35142-05-3

Chemical Properties

Melting Point: 292°C

Boiling Point: 550.1°C at 760 mmHg

Flash Point:210.3°C

Density: 1.442g/cm3

Vapor Pressure: 6.2E-13mmHg at 25°C

Refractive Index: 1.6200 (estimate)

PSA: 64.99000

LogP: 3.42850

Global suppliers and manufacturers of 35142-05-3total 3 suppliers on LookChem

Density: 1.442g/cm³