- Stable Yellow Imidazolium Compounds
-
Described herein is a yellow imidazolium chromophore having a structure according to Formula V.
- -
-
Paragraph 0137; 0138; 0222; 0223; 0236; 0237
(2018/04/13)
-
- 1-HEXYL-1H-PYRAZOLE-4,5-DIAMINE HEMISULFATE, AND ITS USE IN DYEING COMPOSITIONS
-
1-hexyl-1H-pyrazole-4,5-diamine hemisulfate, as represented in formula (IX-a), and its use in oxidative dyeing composition. This pyrazole salt was found to combine good stability as raw material and good shade intensity with a range of common couplers when formulated in hair dyeing composition.
- -
-
Page/Page column 6
(2013/08/28)
-
- Telescoping Synthesis of 5-Amino-4-Nitroso-1-Alkyl-1H-Pyrazole Salt
-
A telescoping synthesis of 5-amino-4-nitroso-1-alkyl-1H-pyrazole salt derivatives of formula (I), the compound (I) itself, and its use as an intermediate in the fabrication of 1-alkyl-4,5-diaminopyrazole salts of general formula (IX). The compounds of formula (IX) can be used as precursor dyes in oxidative hair dye compositions. R is a mono- or poly-substituted or unsubstituted, straight or branched, saturated or mono- or poly-unsaturated, alkyl group. HZ and HZ′ are organic or mineral acids.
- -
-
Paragraph 0053-0055; 0062
(2013/08/28)
-
- TELESCOPING SYNTHESIS OF 5-AMINO-4-NITROSO-1-ALKYL-1H-PYRAZOLE SALTS
-
A telescoping synthesis of 5-amino-4-nitroso-1-alkyl-1H-pyrazole salt derivatives of formula (I), the compound (I) itself, and its use as an intermediate in the fabrication of 1-alkyl-4,5-diaminopyrazole salts of general formula (IX). The compounds of formula (IX) can be used as precursor dyes in oxidative hair dye compositions. R is a mono- or poly- substituted or unsubstituted, straight or branched, saturated or mono-or poly- unsaturated, alkyl group. HZ and HZ' are organic or mineral acids.
- -
-
Page/Page column 10; 11
(2013/08/28)
-
- 1-Hexzl-1H-Pyrazole-4,5-Diamine Hemisulfate, and Its Use in Dyeing Compositions
-
1-hexyl-1H-pyrazole-4,5-diamine hemisulfate, as represented in formula (IX-a), and its use in oxidative dyeing composition. This pyrazole salt was found to combine good stability as raw material and good shade intensity with a range of common couplers when formulated in hair dyeing composition.
- -
-
Paragraph 0025; 0032
(2013/08/28)
-
- Discovery of ectoparasiticidal hydrazonotrifluoromethanesulfonanilides
-
A series of hydrazonotrifluorosulfonanilide derivatives were synthesized and evaluated for in vitro activity against the ectoparasites Ctenocephalides felis and Rhipicephalus sanguineus. Some compounds with excellent activity against tick were identified.
- Ali, Abdelselam,Fisara, Petr,Freemont, Jamie A.,Kyi, Stella,Meyer, Adam G.,Riches, Andrew G.,Sargent, Roger M.,Sawutz, David G.,Turner, Kathleen A.,Winzenberg, Kevin N.,Yang, Qi
-
experimental part
p. 649 - 652
(2010/06/12)
-
- PYRAZOLO (3, 4-B) PYRIDINE DERIVATIVES AS PDE4 INHIBITORS
-
The present invention provides a compound of formula (I) or a salt thereof (in particular, a pharmaceutically acceptable salt thereof): The invention also provides the use of the compounds or salts as inhibitors of phosphodiesterase type IV (PDE4) and/or
- -
-
Page/Page column 110
(2008/06/13)
-
- PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS, AND THEIR USE AS PDE4 INHIBITORS
-
The invention provides a compound of formula (I) or a salt thereof: wherein Ar has the sub-formula (x): and wherein: Q1 is NH or NMe, in which case Q2 is -C(O)-, -S(O)2-, -C(O)NH- or -C(O)NMe-; or Q1 is a bond o
- -
-
Page/Page column 168
(2010/11/30)
-
- Synthesis of 2-benzyl-2H-pyrazole-3,4-diamine dihydrochloride
-
This report describes a straightforward, high yield synthesis of a previously inaccessible N-protected diaminopyrazole in five steps starting from acrylonitrile, hydrazine and benzaldehyde.
- Holschbach, Marcus H.,Wutz, Walter,Olsson, Ray A.
-
-
- 3-[1-(2-Benzoxazolyl)hydrazino]propanenitrile derivatives: Inhibitors of immune complex induced inflammation
-
3-[1-(2-Benzoxazolyl)hydrazino]propanenitrile derivatives were evaluated in the dermal and pleural reverse passive Arthus reactions in the rat. In the pleural test these compounds were effective in reducing exudate volume and accumulation of white blood cells. This pattern of activity was similar to that of hydrocortisone and different from that of indomethacin. The structural requirements for inhibiting the Arthus reactions were studied by systematic chemical modification of 1. These structure-activity relationship studies revealed that nitrogen 1' of the hydrazino group is essential for activity and must be electron rich, whereas chemical modifications of other sites of 1 had only a modest effect on activity.
- Haviv,Ratajczyk,DeNet,Kerdesky,Walters,Schmidt,Holms,Young,Carter
-
p. 1719 - 1728
(2007/10/02)
-
- Hydroxyalkylation with α-Hydroperoxydiazenes. Alcohols from Olefins and Carbonyl Compounds from Enol Ethers
-
Alkyl(1-hydroxy-1-methylethyl)diazenes 2a-f were prepared in solution by autoxidation of the corresponding hydrazones of acetone.Thermolysis of the diazenes at 50-80 deg C in alkenes leads to alcohols.For example, 2b decomposes in 1,1-diphenylethene to afford 5-hydroxy-5,5-diphenylpentanenitrile.Alkenes with abstractable allylic hydrogens gave analogous products, but in very low yield.Thermolysis of a diazene 2 in an enol ether solvent leads to an aldehyde or a ketone.Thus, 2a decomposes in 1-ethoxyethene and in 2-methoxypropene to afford, respectively, 4,4,4-trifluorobutanal and 5,5,5-trifluoro-2-pentanone.Yields lie in range from 50percent to 70percent.The thermolysis of 2 in alkenes involves radical intermediates and radical chain hydroxyalkylation of alkene double bonds.In one chain-propagating step, R*, generated from 2, adds to the alkene.The adduct radical so formed propagates by inducing decomposition of 2 by attack at hydroxyl oxygen.According to this mechanism, initial products from enol ethers are hemiacetals or hemiketals which do not survive the reaction conditions but decompose to the corresponding carbonyl compounds.Preliminary evidence for this mechanism is presented.
- Osei-Twum, Emmanuel Y.,McCallion, Doug,Nazran, Avtar S.,Panicucci, Rick,Risbood, Prabhakar A.,Warkentin, John
-
p. 336 - 342
(2007/10/02)
-
- O-Alkyl-O-[1-cyanoalkyl-5-substituted-mercapto-triazol(3)yl]-(thiono)-phosphoric(phosphonic) acid esters or ester-amides
-
O-Alkyl-O-[1-cyanoalkyl-5-substituted-mercapto-triazol(3)yl]-(thiono)-phosphoric (phosphonic) acid esters or ester-amides of the formula EQU1 in which R is alkyl with 1 to 6 carbon atoms, R' is alkyl, alkoxy or alkylamino each with 1 to 6 carbon atoms, amino or phenyl, R" is alkenyl with 2 to 6 carbon atoms, or alkyl, cyanoalkyl or alkylthioalkyl with 1 to 4 carbon atoms in each alkyl moiety, R'" is cyanoalkyl with 1 to 4 carbon atoms in the alkyl moiety, and X is oxygen or sulfur, Which possess insecticidal, acaricidal and nematocidal properties.
- -
-
-