- Process to Prepare Sucralose
-
The present invention relates to a process to prepare sucralose. More particularly the said process relates to the production of sucralose, chemically known as, 6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-alpha-D-galactopyranoside of formula (1)
- -
-
Page/Page column 4
(2010/08/07)
-
- AN IMPROVED PROCESS FOR THE PREPARATION OF 2, 3, 6, 3 ', 4 ' - PENTA- O -ACETYLSUCROSE
-
The present invention relates to an improved process for the preparation of 2, 3, 6, 3', 4'- Penta-O-acetylsucrose (6-PAS) (V) from sucrose. Formula (V)
- -
-
Page/Page column 6; 10-11
(2009/09/04)
-
- AN IMPROVED PROCESS FOR THE PREPARATION OF 1, 6-DICHLORO-1, 6-DIDE0XY-BETA-D-FRUCT0FURAN0SYL-4-CHL0R0-4-DE0XY-ALPHA-GALACT0PY RANOSIDE
-
The present invention relates to an improved process for the preparation of 2, 3, 6, 3', 4'- Penta-O-acetylsucrose 6-PAS), formula (V) and sucralose, formula (I).
- -
-
Page/Page column 6-8
(2009/09/04)
-
- Novel chlorination process for preparing sucralose
-
A process for preparing a sucralose-6-ester, a key intermediate to sucralose. The process contains (a) creating a heterogeneous mixture comprising a first phase comprising a sucrose-6-ester and a second phase comprising a chlorinating reagent; and (b) reacting the sucrose-6-ester with the chlorinating reagent, to prepare a sucralose-6-ester. In addition, processes for preparing sucralose from sucrose-6-esters are provided.
- -
-
Page/Page column 7
(2009/01/20)
-
- METHOD OF PRODUCING SUCRALOSE
-
A method of producing sucralose is disclosed. The method of producing sucralose comprises the steps of preparing a compound (6, 1', 6'-tri- 0 -tritylsucrosepenta- acetate) by reacting sucrose, which is a starting material, with a tritylating agent to form a reaction product, and then reacting the reaction product with acetic anhydride (step 1); preparing a compound (2, 3, 4, 3', 4'-penta- 0 -acetylsucrose) by reacting the compound prepared in step 1 with hydrogen chloride gas having the same equivalent amount as the compound (step 2); preparing a compound (2, 3, 6, 3', 4'-penta- 0 -acetylsucrose) by isomerizing the compound prepared in step 2, under a base catalyst (step 3); preparing a compound (4, 1', 6'-trichloro- 4, 1', 6'-trideoxy-2, 3, 6, 3', 4'-penta- 0 -acetyl-galactosucrose) by chlorinating the compound prepared in step 3 (step 4); and preparing 4,1, 6'-trichloro-4, 1', 6'-trideoxygalactosucrose by deacetylating the compound prepared in step 4, and then filtering the deacetylated compound using a cation exchange resin (step 5).
- -
-
Page/Page column 10-11
(2008/12/08)
-
- PROCESS FOR THE PREPARATION OF A GLUCOSE DERIVATIVE
-
The present invention relates to an improved, safe, commercially viable, cost effective and eco friendly process for the preparation of 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose (Sucralose). The invention is directed towards the convenient synthesis of 2,3,4,3',4'-penta-O-acetyl sucrose (4-PAS) from 6,1',6'-tri-O-trityl-penta-O-acetyl sucrose ("TRISPA").
- -
-
Page/Page column 29-30; 30
(2010/11/28)
-
- Regioselective Enzymatic Deacetylation of Sucrose Octaacetate in Organic Solvents.
-
The first examples of deacetylation of sucrose octaacetate using proteases and lipases in organic solvents are reported.The regiochemistry of the product sucrose hepta-, hexa- and pentaacetates was established by perdeuteroacetylation and 1H-NMR.Preparation of key intermediates in the commerical synthesis of the high intensity sweetener, sucralose was achieved.
- Palmer, David C.,Terradas, Fernand
-
p. 1673 - 1676
(2007/10/02)
-