- A Re2O7catalyzed cycloetherification of monoallylic diols
-
A Re2O7catalyzed cycloetherification of monoallylic diols is described. The reaction features short reaction time, mild reaction conditions and exclusive E selectivity. A wide range of monoallylic alcohols with alkyl or aryl substituents on olefin smoothly undergo ring closure to deliver corresponding oxa-heterocycles. The reaction is also operationally simple and not sensitive to air and moisture.
- Wan, Xiaolong,Hu, Jiadong,Xu, Dongyang,Shang, Yang,Zhen, Yanxia,Hu, Chenchen,Xiao, Fan,He, Yu-Peng,Lai, Yisheng,Xie, Weiqing
-
p. 1090 - 1093
(2017/03/02)
-
- Atom transfer radical cyclization (ATRC) applied to a chemoenzymatic synthesis of Quercus lactones
-
The natural fragrances (+)-trans whisky lactone 2 and (+)-trans cognac lactone 4, together with a minor amount of their (-)-cis stereoisomers, were prepared in 50% and 42% overall yield, respectively, starting from racemic 1-hepten-3-ol (±)-5 and 1-octen-3-ol (±)-6. The procedure involved first the enantioconvergent, lipase mediated transformation of the secondary allylic alcohols derived dichloroacetates (±)-7 and (±)-8 into the corresponding homochiral (+)-7 and (+)-8, combined with their cyclization under a transition metal catalyzed atom transfer process.
- Felluga, Fulvia,Forzato, Cristina,Ghelfi, Franco,Nitti, Patrizia,Pitacco, Giuliana,Pagnoni, Ugo Maria,Roncaglia, Fabrizio
-
p. 527 - 536
(2007/10/03)
-