- Process for producing 3,5-difluoroaniline and derivative thereof
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A process for production of a 3,5-difluoroaniline compound with ease is disclosed, which comprise reacting an aminating agent with a 1,3,5-trifluorobenzene compound.
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- Process for producing 3,5-difluoraniline
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A process for producing 3,5-difluoroaniline, which comprises reacting a benzonitrile compound of the formula (I): STR1 wherein each of X1, X2 and X3 is hydrogen, chlorine, bromine or a cyano group, provided that at least one of X1 to X3 is a cyano group, with a mineral acid for hydrolysis and decarboxylation to obtain an aniline compound of the formula (II): STR2 wherein each of X4, X5 and X6 is hydrogen, chlorine or bromine, provided that at least one of X4 to X6 is hydrogen, and in the case of a compound of the formula (II) wherein X4, X5 and X6 are not simultaneously hydrogen, reacting such a compound with hydrogen in a presence of a catalyst for reduction to obtain 3,5 -difluoroaniline.
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- PRODUCTION OF 2-HALO-3,5-DIFLUOROANILINE, INTERMEDIATE FOR PRODUCING THE SAME, AND PRODUCTION OF SAID INTERMEDIATE
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A process for producing 2-halo-3,5-difluoroaniline by heating 4-amino-5-halo-2,6-difluoroisophthalonitrile in the presence of sulfuric acid with a concentration of 50 wt.% or above at a temperature ranging from 80 °C to the boiling point of the reaction m
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