Substrate scope and stereocontrol in the Rh(II)-catalysed oxyamination of allylic carbamates
Application of a modified Du Bois protocol for rhodium-stabilised nitrenoid generation to a variety of allylic carbamates results in 4-acetoxymethyl-1,3-oxazolidin-2-one derivatives with moderate to high levels of stereocontrol.
Unsworth, William P.,Lamont, Scott G.,Robertson, Jeremy
p. 7388 - 7394
(2017/09/12)
Metal-free intramolecular aziridination of allylic carbamates mediated by hypervalent iodine compounds
An efficient and practical hypervalent iodine compound mediated metal-free intramolecular aziridination reaction of allylic carbamates was developed. Analytically pure aziridines were obtained in high yields by simple filtration of the reaction mixture. I