BRANCHED OR MACROCYCLIC POLYAMINES AND USES THEREOF
The present invention relates to synthetic polyamines and their polyammonium derivatives and their use as a pharmacological or biological research tool or as a therapeutic agent.
-
Page/Page column 53; 54
(2014/03/25)
Molecular loop lock: A redox-driven molecular machine based on a host-stabilized charge-transfer complex
A cyanine dye having the structure has an overall positive charge greater than ±1, by virtue of the presence of one to five positively charged N or P or S atoms, and also has a reactive or functional group by which it may be linked to a biomolecule or a solid surface.
-
Example 1
(2010/01/30)
Synthesis of N-quaternary ammonium [3H] and [(99m)Tc]Polyazamacrocycles, potential radiotracers for cartilage imaging
The [3H] and [(99m)Tc] synthesis of three new compounds, N-[3-(pyridinio)propyl] cyclam (NPPC), N-[3-(triethylammonium)propyl] cyclam (NTPC) and N-[3-(triethylammonium)propyl]-15ane-N5 (NTP 15-5), potential tracers for cartilage, is reported. NPPC and NTPC were labelled with tritium on the ethyl group of cyclam with a specific radioactivity of 89 MBq/mmol. The [(99m)Tc]-labelling of the three quaternary ammonium chelates was realized with a high specific activity in the range 20-25 MBq/μmol.
Squarate dyes and their use in fluorescent sequencing method
Novel squarate dyes are described, and adducts of these dyes with biologically significant chemical species such as nucleosides or nucleotides. The adducts have useful properties for fluorescent nucleic acid sequencing methods.
-
(2008/06/13)
Search for the pharmacophore of bispyridinium-type allosteric modulators of muscarinic receptors
The bis(dichlorobenzyl) ether of the bispyridinium oxime TMB 4 stabilizes antagonist binding to M2-cholinoceptors which is indicative of an allosteric action. More than 10 derivatives of the lead compound were synthesized to investigate structu
Cid,Holzgrabe,Kostenis,Mohr,Trankle
p. 1439 - 1445
(2007/10/02)
The Quarternisation of Tertiary Amines with Dihalomethane
Whereas dichloromethane is inert towards reaction with most tertiary amines under atmospheric conditions, it readily reacts with a wide variety at high pressures to produce α-chloro quaternary ammonium and even bis-ammonium salts.The reaction of dichloromethane and dibromomethane with eleven tertiary amines and properties of the products are described.
Almarzoqi, B.,George, A. V.,Isaacs, N. S.
p. 601 - 608
(2007/10/02)
More Articles about upstream products of 3720-84-1