A Short synthesis of benzomorphane analgesics (±)-Metazocine and (±)-Phenazocine
A three step synthesis of (±)-metazocine and (±)-phenazocine starting with 3,4-lutidine is described. The key step involves Lewis acid promoted lithiation/electrophilic substitution reaction of N-alkyl-3,4-dimethyl- 1,2,5,6- tetrahydropyridine. Copyright
Singh, Kamal Nain,Singh, Pushpinder,Sharma, Arvind Kumar,Singh, Paramjit,Kessar, Satinder V.
experimental part
p. 3716 - 3720
(2010/12/29)
An improved resolution of (±)-cis-N-normetazocine
-
Brine,Berrang,Hayes,Carroll
p. 2139 - 2143
(2007/10/02)
More Articles about upstream products of 3734-52-9