Synthesis of idebenone; a synthetic analog of coenzyme Q
Idebenone, a synthetic analog of coenzyme Q, was prepared from the tetramethoxytoluene 2. Two main transformations in this procedure are Friedel-Crafts acylation of 2 to 4 and CAN assisted oxidation of 7 to the quinone 8.
Jung,Joe,Seong,Park
p. 2735 - 2741
(2007/10/03)
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