STUDIES ON FRIEDEL-CRAFTS ACYLATION OF N-ACETYLHOMOVERATRYLAMINE AND PREPARATION OF 1-SUBSTITUTED 3,4-DIHYDRO-6,7-DIMETHOXYISOQUINOLINES
Friedel-Crafts acylation of N-acetylhomoveratrylamine in a molar ratio of 1:2:3 of 1, AlCl3 and the appropriate acid chloride using nitrobenzene as solvent gave the corresponding 2-acyl derivatives 2a-j in good yields.Subsequent treatment of 2 in boiling