Stereoselective synthesis of Z and E 3-F-alkyl 2-propenoates and derivatives
The stereoselective preparation of 3-F-alkyl 2-propenoates and their derivatives is described.E-isomers are easily obtained by an in situ reduction-olefination from esters of F-acids and phosphonates or by a convenient dehydration of 3-F-alkyl 3-hydroxyesters.Z-isomers are known to be prepared by the hydrogenation of alkynes. - Keywords: Unsaturated ester; Unsaturated nitrile; F-Alkyl Chain; Dehydration; F-Enoyl sultam
Lanier Marion,Pastor, Raphaeel
p. 35 - 40
(2007/10/03)
Stereoselective synthesis of F-alkyl α,β-unsaturated esters and their epoxidation
Strong electrophilic Z and E 3-F-alkyl 2-propenoates have been prepared stereoselectively. Their extremely difficult epoxidation has been achieved with retention of stereochemistry using t-BuO2Li, leading to F-alkyl glycidic esters, which are useful building blocks for the synthesis of new amphiphiles.
Lanier,Haddach,Pastor,Riess
p. 2469 - 2472
(2007/10/02)
More Articles about upstream products of 37759-80-1