Synthesis and anti cervical cancer activity of novel 5H-thiochromeno [4,3-d]pyrimidines
A series of novel 5H-Thiochromeno[4,3-d]pyrimidine derivatives were synthesized, purified and characterized by different spectroscopy techniques such as1H NMR,13C NMR, Mass and Elemental Analysis. The new compounds were evaluated for their anti-cervical cancer activity on Human Cervical Cell Line HeLa. They were found to be potent anti-cervical cancer agents with GI50 values less than 10 μg/mL with respect to positive control drug Adriamycin.
Naliapara, Yogesh,Pandya, Dhananjay
p. 294 - 302
(2020/04/21)
Towards room temperature ionic liquid crystals: Linear versus bent imidazolium phenylpyrimidines
The synthesis and the mesomorphic properties of novel imidazolium salts with mesogenic 2-phenylpyrimidine or 2-alkylpyrimidinecarboxylic acid central cores are reported. The mesogenic units are connected to the imidazolium head groups via an alkoxy spacer