- A multifunctional luminescent network film electrochemically deposited from a new AIEE emitter for OLEDs and explosive detection
-
Electrochemical polymerization (EP) has attracted considerable attention because of its high material utilization, simple process and low cost. In this work, a new AIEE-active blue-emitting molecule, TCzDPAn, was synthesized. The multifunctional luminesce
- Hao, Hongmin,Luo, Haiyuan,Yi, Aihua,Liu, Cong,Xu, Bingjia,Shi, Guang,Chi, Zhenguo
-
-
Read Online
- Synthesis of α-Aryldiazophosphonates via a Diazo Transfer Reaction
-
The simple synthetic procedure for preparation of α-aryl-α-diazophosphonates via a diazo transfer reaction is proposed. Benzylphosphonates reacted with tosyl azide (TsN3) in the presence of potassium tert-butoxide (KOtBu) to afford diazophosphonates in a yield up to 79%. The proposed method is general. The reaction uses easily available starting materials, tolerates various functional groups, and may be applied for multi-gram scale synthesis.
- Beletskaya, Irina P.,Titanyuk, Igor D.
-
p. 2748 - 2757
(2022/03/14)
-
- A new insight into the push-pull effect of substituents via the stilbene-like model compounds
-
In this paper, authors report on 1-pyridyl-2-arylethenes, 1-furyl-2-arylethylenes, 1,2-diphenylpropylenes and substituted cinnamyl anilines as stilbene-like model compounds to investigate the factors dominating the push-pull effect of substituents via usi
- Cao, Chaotun,Cao, Chenzhong,Zeng, Zhao
-
-
- Selective esterification of phosphonic acids
-
Here, we report straightforward and selective synthetic procedures for mono-and diesteri-fication of phosphonic acids. A series of alkoxy group donors were studied and triethyl orthoacetate was found to be the best reagent as well as a solvent for the performed transformations. An important temperature effect on the reaction course was discovered. Depending on the reaction temperature, mono-or diethyl esters of phosphonic acid were obtained exclusively with decent yields. The sub-strate scope of the proposed methodology was verified on aromatic as well as aliphatic phosphonic acids. The designed method can be successfully applied for small-and large-scale experiments without significant loss of selectivity or reaction yield. Several devoted experiments were performed to give insight into the reaction mechanism. At 30?C, monoesters are formed via an intermediate (1,1-diethoxyethyl ester of phosphonic acid). At higher temperatures, similar intermediate forms give diesters or stable and detectable pyrophosphonates which were also consumed to give diesters.31P NMR spectroscopy was used to assign the structure of pyrophosphonate as well as to monitor the reaction course. No need for additional reagents and good accessibility and straightforward purification are the important aspects of the developed protocols.
- Brodzka, Anna,Koszelewski, Dominik,Ostaszewski, Ryszard,Trzepizur, Damian
-
-
- Selective hydrolysis of phosphorus(v) compounds to form organophosphorus monoacids
-
An azide and transition metal-free method for the synthesis of elusive phosphonic, phosphinic, and phosphoric monoacids has been developed. Inert pentavalent P(v)-compounds (phosphonate, phosphinate, and phosphate) are activated by triflate anhydride (Tf2O)/pyridine system to form a highly reactive phosphoryl pyridinium intermediate that undergoes nucleophilic substitution with H2O to selectively deprotect one alkoxy group and form organophosphorus monoacids.
- Ash, Jeffrey,Cordero, Paula,Huang, Hai,Kang, Jun Yong
-
p. 6007 - 6014
(2021/07/21)
-
- Nickel-Catalyzed N, N-Diarylation of 8-Aminoquinoline with Large Steric Aryl Bromides and Fluorescence of Products
-
A simple and efficient methodology for the synthesis of large sterically hindered triarylamines in a single step was developed. A direct N,N-diarylation of 8-aminoquinoline with sterically hindered bromides, making use of inexpensive nickel as a catalyst and simple sodium salt as a base, gives the products in good to excellent yields. Various bromides and substituted 8-aminoquinolines are tolerated. Preliminary fluorescence results indicate that these sterically hindered and conjugated triarylamines may have some potential in material chemistry.
- Yan, Mingpan,Zhu, Longzhi,Zhang, Xingxing,Yin, Shuang-Feng,Kambe, Nobuaki,Qiu, Renhua
-
supporting information
p. 2514 - 2520
(2021/04/13)
-
- Determination and application of the excited-state substituent constants of pyridyl and substituted phenyl groups
-
Thirty six 1-pyridyl-2-arylethenes XCH=CHArY (abbreviated XAEY) were synthesized, in which, X is 2-pyridyl, 3-pyridyl and 4-pyridyl and Y is OMe, Me, H, Br, Cl, F, CF3, and CN. Their ultraviolet absorption spectra were measured in anhydrous ethanol, and their wavelengths of absorption maximum λmax were recorded. Also, the 234 λmax values of 1-substituted phenyl-2-arylethylene compounds (XAEY, where X is substituted phenyl) were collected. The excited-state substituent constants (Formula presented.) of three pyridyl groups and 23 substituted phenyl groups (total of 26) were obtained by means of curve-fitting method. Taking the λmax values of 358 samples of bi-arylethene derivatives as a data set and 126 samples of bi-aryl Schiff bases (including nine compounds synthesized by this work) as another data set, quantitative correlation analyses were performed by employing the obtained (Formula presented.) as a parameter, and good results were obtained for the two data sets. The reliability of the obtained (Formula presented.) values was verified. The results of this paper can provide excited-state substituent constants for the study and application of optical properties of conjugated organic compounds containing aryl groups.
- Cao, Chao-Tun,Yan, Lu,Cao, Chenzhong
-
-
- Aggregation-induced light-emitting compound and preparation method and application thereof
-
The invention discloses an aggregation-induced light-emitting compound as well as a preparation method and application thereof. The compound is a carbazole derivative of spirobifluorene and is formedby connecting a triphenylethylene derivative and a spiro
- -
-
Paragraph 0049-0050; 0053-0054; 0069
(2020/05/05)
-
- Effects of incorporating regioisomers and flexible rotors to direct aggregation induced emission to achieve stimuli-responsive luminogens, security inks and chemical warfare agent sensors
-
Efficient transformation of ACQ materials to AIE luminogens using simple design principles of positional isomerization and C-C bond exclusion is presented here. Consequently, the bond link, position and packing influence the photophysical properties that can be utilized in erasable secret inks, pressure sensors and chemical warfare sensors.
- Adil, Laxmi Raman,Iyer, Parameswar Krishnan
-
supporting information
p. 7633 - 7636
(2020/07/21)
-
- Transition metal-free access to 3,4-dihydro-1,2-oxaphosphinine-2-oxides from phosphonochloridates and chalcones through tandem Michael addition and nucleophilic substitution
-
A novel and transition metal-free synthesis of 3,4-dihydro-1,2-oxaphosphinine 2-oxides was developed. LiHMDS-mediated tandem Michael addition and nucleophilic substitution of readily available phosphonochloridates and chalcones afforded a variety of valuable 3,4-dihydro-1,2-oxaphosphinine 2-oxides bearing diverse functionalities in excellent yields and satisfactory to good diastereoselectivity (up to 99% yield and up to 99?:?1 dr).
- Fu, Zhicheng,Sun, Simin,Yang, Anjian,Sun, Fang,Xu, Jiaxi
-
supporting information
p. 13124 - 13127
(2019/11/11)
-
- Novel phenanthrene compounds, a method of making the same and organic electronic devices using the same
-
The present invention relates to novel phenanthrene compounds having excellent luminous efficiency and lifespan, a manufacturing method thereof, and an organic electronic device including the novel phenanthrene compounds. The novel phenanthrene compounds according to the present invention can form steric conformation, can improve performance through improvement of electronic density, also can improve performance by regulating the molecular weight and position of a functional group because the molecular weight of the compounds is low, and can minutely regulate luminous wavelength and improve performance according to types of the functional groups. As the result, the organic electronic device including the novel phenanthrene compounds has high brightness, excellent thermal resistance, long lifespan, and high efficiency.
- -
-
Page/Page column 21; 22; 29; 30; 31; 35; 37
(2019/10/22)
-
- Novel compound and organic electroluminescent device adopting novel compound
-
The invention provides an organic electroluminescent device. The organic electroluminescent device comprises a first electrode, a second electrode and one or more organic layers, wherein the organic layer contains at least one compound represented by a fo
- -
-
Paragraph 0062; 0069; 0070
(2019/07/04)
-
- Alcohol-based Michaelis-Arbuzov reaction: An efficient and environmentally-benign method for C-P(O) bond formation
-
The famous Michaelis-Arbuzov reaction is extensively used both in the laboratory and industry to manufacture tons of widely-used organophosphoryl compounds every year. However, this method and the modified Michaelis-Arbuzov reactions developed recently still have some limitations. We now report a new alcohol-version of the Michaelis-Arbuzov reaction that can provide an efficient and environmentally-benign method to address the problems of the known Michaelis-Arbuzov reactions. That is, a wide range of alcohols can readily react with phosphites, phosphonites, and phosphinites to give all the three kinds of phosphoryl compounds (phosphonates, phosphinates, and phosphine oxides) using an n-Bu4NI-catalyzed efficient C-P(O) bond formation reaction. This general method can also be easily scaled up and used for further synthetic transformations in one pot.
- Ma, Xiantao,Xu, Qing,Li, Huan,Su, Chenliang,Yu, Lei,Zhang, Xu,Cao, Hongen,Han, Li-Biao
-
supporting information
p. 3408 - 3413
(2018/08/06)
-
- Direct Aryloxylation/Alkyloxylation of Dialkyl Phosphonates for the Synthesis of Mixed Phosphonates
-
A strategy for the direct functionalization strategy of inertial dialkyl phosphonates with hydroxy compounds to afford diverse mixed phosphonates with good yields and functional-group tolerance has been developed. Mechanistic investigations involving both NMR studies and DFT studies suggest that an unprecedented highly reactive PV species (phosphoryl pyridin-1-ium salt), a key intermediate for this new synthetic transformation, is generated in situ from dialkyl phosphonate in the presence of Tf2O/pyridine.
- Huang, Hai,Denne, Johanna,Yang, Chou-Hsun,Wang, Haobin,Kang, Jun Yong
-
p. 6624 - 6628
(2018/05/14)
-
- Synthesis, characterization and properties of titanium phosphonate clusters
-
Titanium phosphonate clusters were synthesized by the reactions of titanium tetraisopropoxide (Ti(OiPr)4) with arylphosphonic acids (ArPO3H2, Ar = Ph, 1-Nap, 4-MeOPh, 4-FPh, 4-ClPh, 4-BrPh, and 4-BrBn) and H2O in tetrahydrofuran (THF) at room temperature. [Ti4(μ3-O)(OiPr)5(μ-OiPr)3(O3PAr)3]·solv (Ar = Ph (1), 1-Nap (2), 4-MeOPh (3), 4-FPh (4), 4-ClPh (5); solv = thf for 1 and 2 or 2-propanol for 3–5) were isolated as new Ti4P3-type clusters, while Ti7(μ3-O)2(OiPr)6(μ-OiPr)6(O3PBnBr)6 (6) was isolated as a Ti7P6-type cluster. A co-crystal of Ti4P3- (7a) and Ti7P6-type (7b) clusters were obtained when 4-BrPhPO3H2 was used, and [Ti(OiPr)(acac)(O3PPh)]4 (8), a new cage cluster, was obtained when Ti(acac)2(OiPr)2 (Hacac = acetylacetone) was reacted with PhPO3H2.
- Hayami, Ryohei,Sagawa, Takuya,Tsukada, Satoru,Yamamoto, Kazuki,Gunji, Takahiro
-
supporting information
p. 1 - 8
(2018/04/02)
-
- Detecting live bacteria instantly utilizing AIE strategies
-
A new class of biosensor molecules evoking fluorescent emission by rotation-restricted binding with bacteria was examined for its applicability in detecting live bacteria instantly. The fluorogens possessed multiple tetraphenylethene (TPE)-cored boronic a
- Kong, Ting Ting,Zhao, Zheng,Li, Ying,Wu, Fei,Jin, Tuo,Tang, Ben Zhong
-
p. 5986 - 5991
(2018/10/08)
-
- Multifunctional aggregation-induced luminescence enhancement compound, method for preparing same and application of multifunctional aggregation-induced luminescence enhancement compound
-
The invention discloses a multifunctional aggregation-induced luminescence enhancement compound, a method for preparing the same and application of the multifunctional aggregation-induced luminescenceenhancement compound. The multifunctional aggregation-i
- -
-
Paragraph 0077; 0079; 0080
(2018/12/02)
-
- Synthetic method for alkyl group phosphorous acid diester compounds or alkyl group phosphinic acid ester compounds
-
The invention discloses a synthetic method for alkyl group phosphorous acid diester compounds or alkyl group phosphinic acid ester compounds. According to the synthetic method, alcohols which are cheap, easy to get, wide in source, stable and low in toxicity serve as alkylating reagents, iodine salt which is cheap and easy to get serves as catalysts, no solvent is needed, and the alkyl group phosphorous acid diester compounds can be selectively directly obtained after a reaction. The reaction method is simple, the condition is mild, no organic solvent is needed and operation is simple. According to the method, the requirements for reaction conditions are low, various types of alcohols such as a benzyl group type, an allyl type and a fat type can be utilized as the alkylate reagents to implement the synthesis of different types of substituted alkyl group phosphorous acid diester, and the method can be further expanded to the synthesis of the alkyl group phosphinic acid ester compounds through the reaction between the substituted phosphonous acid diester and the alcohols.
- -
-
Paragraph 0030; 0031; 0032; 0033
(2017/04/26)
-
- Two trans-1-(9-anthryl)-2-phenylethene derivatives as blue-green emitting materials for highly bright organic light-emitting diodes application
-
1-(9-Anthryl)-2-phenylethene (t-APE) is a blue-green material with high fluorescence quantum yield (Фf 0.44). However, it is easily crystallized. Herein, Two asymmetric blue-green emitting materials based on t-APE, (E)-9-(4-(2-(anthracen-9-yl)vinyl)phenyl)-10-(naphthalen-1-yl)anthracene (6) and (E)-9-(4-(2-(anthracen-9-yl)vinyl)phenyl)-10-(naphthalen-2-yl)anthracene (7) were firstly designed and synthesized. The two compounds possess high thermal stability, morphological durability, and bipolar characteristics. The non-doped blue-green organic light-emitting diodes (OLEDs) using 6 and 7 as emitting layers showed emission at 495 nm, full width at half maximum of 80 nm, maximum brightness of 13,814, 10,579 cd m?2, maximum current efficiency of 3.62, 7.16 cd A?1, and Commission Internationale de L'Eclairage (CIE) coordinate of (0.20, 0.43), respectively. Furthermore, when employing 6 and 7 as blue-green emitting layers and rubrene doped in tris-(8-hydroxyquinolinato)aluminum (Alq3) as the orange emitting layers to fabricate white OLEDs (WOLEDs), the WOLEDs exhibit a maximum brightness of 10,984, 14,652 cd m?2, maximum current efficiency of 2.04, 2.70 cd A?1, and CIE coordinate of (0.30, 0.40), (0.37, 0.47), Color Rendering Index (CRI) of 65, 60, stable EL spectra, respectively. This study demonstrates that the t-APE-type derivatives have the excellent properties for the emitting materials of OLEDs.
- Zhou, Nonglin,Shao, Xiaona,Wang, Shirong,Xiao, Yin,Li, Xianggao
-
p. 228 - 238
(2017/08/08)
-
- Vinyl-triarylated amine conjugated charge transportation material and preparation method thereof
-
The invention discloses a vinyl-triarylated amine conjugated charge transportation material and a preparation method thereof. The chemical structural formula of the vinyl-triarylated amine conjugated charge transportation material is shown in the formula
- -
-
Paragraph 0092
(2017/07/21)
-
- Dipolar NLO Chromophores Bearing Diazine Rings as π-Conjugated Linkers
-
The synthesis of a series of push-pull derivatives bearing triphenylamine electron-donating group, cyclopenta[c]thiophen-4,6-dione electron acceptor and various π-linkers including (hetero)aromatic fragments is reported. All target chromophores with systematically varied π-linker structure were further investigated by electrochemistry, absorption measurements, and EFISH experiments in conjunction with DFT calculations. Based on electrochemical and photophysical measurements, when a polarizable 2,5-thienylene moiety is embedded into the chromophore π-backbone the highest intramolecular charge transfer (ICT) is observed. Benzene, pyrimidine, and pyridazine derivatives exhibit lower polarizability and extent of the ICT across these π-linkers. The elongation of the π-conjugated system via additional ethenylene linker results in a significant reduction of the HOMO-LUMO gap and an enhancement of the NLO response. Whereas it does not significantly influence electrochemical and linear optical properties, the orientation of the pyrimidine ring seems to be a key parameter on the μβ value due to significant variation of the dipolar moment (μ) value. In 2a and 2c, pyrimidine is oriented to behave as an acceptor and thus generate dipolar molecule with μ above 5 D, whereas in 2b and 2d ground state dipole moment is significantly reduced. This study seems to indicate a high aromaticity of pyrimidine and pyridazine derivatives, close to the benzene analogues and significantly higher than thiophene analogues.
- Klikar, Milan,Le Poul, Pascal,Ru?i?ka, Ale?,Pytela, Old?ich,Barsella, Alberto,Dorkenoo, Kokou D.,Robin-Le Guen, Fran?oise,Bure?, Filip,Achelle, Sylvain
-
p. 9435 - 9451
(2017/09/23)
-
- Influence of the methyl group at C=C bridging bond of stilbene on the longest wavelength maximum in ultraviolet absorption spectra
-
The compounds stilbenes XArCH=CHArY(XSBY) and 1,2-diphenylpropylenes XArC(Me)=CHArY(XSMBY) have bridging groups CH=CH and C(CH3)=CH, respectively, in which the C(CH3)=CH has a side-group CH3 at the carbon-carbon double bond. A series of XSMBY were synthesized, and their longest wavelength maximum λmax (nm) in ultraviolet absorption spectra were measured in this work. We investigated the change regularity of the νmax (cm-1, νmax?=?1/λmax) of XSMBY and compared it with that of XSBY. The results indicate that (1) there is no good linear relationship between the νmax of XSMBY and that of XSBY. (2) Because of the influence of the side-group CH3, in case of the same couple of groups X and Y, the λmax of XSMBY is shorter than that of XSBY, that is, it has a blue shift. (3) The cross-interaction between the side-group CH3 and Y has an important effect on the νmax of XSMBY, while the cross-interaction between the side-group CH3 and X has a little effect on the νmax and can be ignored. (4) The specific cross-interaction between X and Y has important effect on the νmax of XSMBY, whereas it has no important effect on the νmax of XSBY.
- Zhang, Yanxiu,Cao, Chao-Tun,Zhang, Jingyuan,Cao, Chenzhong
-
supporting information
(2017/09/30)
-
- Dual roles for promoting monomers to polymers: A conjugated sulfonium salt photoacid generator as photoinitiator and photosensitizer in cationic photopolymerization
-
An efficient strategy for comprehensive utilization of the conjugated sulfonium salt photoacid generator (PAG), namely, 3-{4-[4-(4-N,N′-diphenylamino)-styryl]phenyl}phenyl dimethyl sulfonium hexafluoroantimonate, was developed through photoinitiated cationic photopolymerization (CP) of epoxides and vinyl ether upon exposure to near-UV and visible light-emitting diodes (LEDs; e.g., 365, 385, 405, and 425 nm). Photochemical mechanisms were investigated by UV–vis spectra, molecular orbital calculations, fluorescence, cyclic voltammetry, and electron spin resonance spin-trapping analyses. Compared with commercial PAGs, the prepared conjugated sulfonium salt generated H+, which can be used as photoinitiator. Moreover, the fluorescent byproducts from photodecomposition can be used as photosensitizer of commercial iodonium salt in the photoinitiating systems of CP. These novel D-π-A type sulfonium-based photoinitiating systems are efficient (epoxide conversion = 85–90% and vinyl conversion >90%; LEDs upon exposure to 365–425 nm) even in low-concentration initiators (1%, w/w) and low curing light intensities (10–40 mW cm?2).
- Jin, Ming,Wu, Xingyu,Malval, Jean Pierre,Wan, Decheng,Pu, Hongting
-
p. 2722 - 2730
(2016/07/28)
-
- Conjugated type sulfonium salt photoinitiator with double functions of photoinitiator and photosensitizer, preparation method and application of conjugated type sulfonium salt photoinitiator
-
The invention relates to a conjugated type sulfonium salt photoinitiator with double functions of a photoinitiator and a photosensitizer, a preparation method and an application of the conjugated type sulfonium salt photoinitiator. The conjugated type sulfonium salt photoinitiator is applicable to excitation from near ultraviolet regions with wavelength of 313 nm, 365 nm, 385 nm, 405 nm and 425 nm to a visible region, so that efficient polymerization of various monomers is initiated; synthesis steps of the photoinitiator are simple, the purification is easy, the yield is high, and in the region of 300 nm-425 nm, the optical absorption property is good and the initiation efficiency is high; a product obtained after decomposition can further be taken as the photosensitizer and combined with commercial photoinitiators such as iodonium salt, sulfonium salt and the like to form an efficient photosensitization-initiated binary polymerization system, and the polymerization efficiency is higher; according to the application of the conjugated type sulfonium salt photoinitiator and photosensitizer to a photopolymerization system, cheap LEDs can be taken as excitation light sources in the near ultraviolet region-visible region, the initiating system has the advantages of low addition quantity, high initiation efficiency and wide light source application range, and resource conservation can be realized.
- -
-
-
- Organic electronic material
-
The present invention discloses an “organic light-emitting device (OLED)”, comprising an anode, a cathode, and one or more organic layers, wherein the said organic layer contains at least one compound having the formula (I), and the said OLED has the advantages of excellent light-emitting efficiency, excellent color purity and long lifetime.
- -
-
Paragraph 0051; 0055
(2016/10/10)
-
- Modular Synthesis of Elongated Phosphonate Bipyridines
-
The synthesis and the photophysical properties of a series of bpy-R2 derivatives L1-L3 (bpy = 2,2′-bipyridine, R represents the substitution at the 4- and 4′-positions of the bpy) are described. R includes phosphonic ester groups as precursors for potent phosphonate anchoring groups, which enable immobilization on transition metal oxide semiconductor surfaces for applications like dye-sensitized solar cells (DSSCs) or dye-sensitized photoelectrosynthesis cells (DSPECs). The ligands L1-L3 differ in the length of conjugated linker units between bpy core and anchoring groups. Phenylene and triazole moieties serve as building blocks for linker elongation. The resulting adjustability of the distance between semiconductor and chromophore represents a viable route to improve cell efficiency, as it will allow tuning of charge carrier recombination and dye aggregation. Furthermore the photophysical studies of the free ligands reveal a pronounced effect of the aryl substitution. The solid-state structures of L1 and L2 are reported within this contribution, enabling the determination of distances between bipyridine nitrogen donor and anchoring group.
- Braumüller, Markus,Sorsche, Dieter,Wunderlin, Markus,Rau, Sven
-
p. 5987 - 5994
(2015/09/22)
-
- A Bulk Dielectric Polymer Film with Intrinsic Ultralow Dielectric Constant and Outstanding Comprehensive Properties
-
A bulk dielectric polymer film with an intrinsic ultralow k value of 1.52 at 10 kHz has been successfully synthesized based on a novel polyimide FPTTPI. More importantly, such outstanding dielectric properties remain stable up to 280 °C. The excellent ultralow dielectric properties are mainly because of the larger free volume (subnanoscale), which intrinsically exists in the amorphous region of polymeric materials. Meanwhile, FPTTPI also shows excellent thermal stability and mechanical properties, with a glass-transition temperature (Tg) of 280 °C, 5 wt % loss temperature of 530 °C, and a residual of 63% at 800 °C under N2. It was soluble in common solvents, which made it possible to undergo simple spin-on or efficient, low-cost, and continuous roll-to-roll processes.
- Liu, Yiwu,Qian, Chao,Qu, Lunjun,Wu, Yunan,Zhang, Yi,Wu, Xinhui,Zou, Bing,Chen, Wenxin,Chen, Zhiquan,Chi, Zhenguo,Liu, Siwei,Chen, Xudong,Xu, Jiarui
-
p. 6543 - 6549
(2015/10/28)
-
- Synergy between twisted conformation and effective intermolecular interactions: Strategy for efficient mechanochromic luminogens with high contrast
-
A strategy towards efficient mechanochromic luminogens with high contrast is developed. The twisted propeller-like conformations and effective intermolecular interactions not only endow the luminogens with AIE characteristics and high efficiency in the crystalline state, but also render them to undergo conformational planarization and disruption in intermolecular interactions upon mechanical stimuli, resulting in remarkable changes in emission wavelength and efficiency. Copyright
- Yuan, Wang Zhang,Tan, Yeqiang,Gong, Yongyang,Lu, Ping,Lam, Jacky W. Y.,Shen, Xiao Yuan,Feng, Cunfang,Sung, Herman H-Y.,Lu, Yawei,Williams, Ian D.,Sun, Jing Zhi,Zhang, Yongming,Tang, Ben Zhong
-
p. 2837 - 2843
(2013/07/28)
-
- Reductive coupling reactions: A new strategy for C(sp3)-P bond formation
-
The C(sp3)-P bond forming reaction utilizing N-tosylhydrazones as readily available alkylating reagents was developed, which provides a new opportunity for preparing phosphine oxide derivatives with moderate to good yields. This reductive coupling reaction is proposed to proceed through an insertion of copper carbene into P-H bond of H-phosphorus oxides. The salient features of the reaction are operational simplicity and functional-group tolerance.
- Chen, Zi-Sheng,Zhou, Zhao-Zhao,Hua, Hui-Liang,Duan, Xin-Hua,Luo, Jian-Yi,Wang, Jia,Zhou, Ping-Xin,Liang, Yong-Min
-
p. 1065 - 1068
(2013/02/25)
-
- DERIVATIVES HAVING VINYL GROUP AND ITS USE IN ELECTROLUMINESCENT ELEMENT
-
The present invention relates to imidazole derivatives having vinyl group represented by general formula (I) which possess electron transporting character, have a high glass transition temperature (Tg), and high decomposition temperature (Td): wherein all symbols are defined as recited in the specification. The present invention also relates to a use of the imidazole derivatives having vinyl group as a guest emitter or electron transporter in luminescent elements.
- -
-
Paragraph 0041; 0042; 0043; 0044
(2013/03/26)
-
- COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS
-
The present invention provides compounds of formula (1) and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, m, n, p, q, Q1, Q2, Q3, Q4, Q5, Q6, X1, X2, X3, X4, A1 and L1, are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
- -
-
Page/Page column 33
(2013/03/26)
-
- Designing anti-inflammatory drugs from parasitic worms: A synthetic small molecule analogue of the acanthocheilonema viteae product ES-62 prevents development of collagen-induced arthritis
-
In spite of increasing evidence that parasitic worms may protect humans from developing allergic and autoimmune diseases and the continuing identification of defined helminth-derived immunomodulatory molecules, to date no new anti-inflammatory drugs have been developed from these organisms. We have approached this matter in a novel manner by synthesizing a library of drug-like small molecules based upon phosphorylcholine, the active moiety of the anti-inflammatory Acanthocheilonema viteae product, ES-62, which as an immunogenic protein is unsuitable for use as a drug. Following preliminary in vitro screening for inhibitory effects on relevant macrophage cytokine responses, a sulfone-containing phosphorylcholine analogue (11a) was selected for testing in an in vivo model of inflammation, collagen-induced arthritis (CIA). Testing revealed that 11a was as effective as ES-62 in protecting DBA/1 mice from developing CIA and mirrored its mechanism of action in downregulating the TLR/IL-1R transducer, MyD88. 11a is thus a novel prototype for anti-inflammatory drug development.
- Al-Riyami, Lamyaa,Pineda, Miguel A.,Rzepecka, Justyna,Huggan, Judith K.,Khalaf, Abedawn I.,Suckling, Colin J.,Scott, Fraser J.,Rodgers, David T.,Harnett, Margaret M.,Harnett, William
-
p. 9982 - 10002
(2014/01/17)
-
- A novel click-chemistry approach to flame retardant polyurethanes
-
The low thermo-oxidative properties of PU foams somewhat limits their practical application, particularly as heat sensitive materials. The introduction of a covalently linked flame retardant organophosphonate ester into the PU foam was achieved using the
- Borreguero, Ana M.,Sharma, Pallavi,Spiteri, Christian,Velencoso, María M.,Carmona, Manuel S.,Moses, John E.,Rodríguez, Juan F.
-
p. 1207 - 1212
(2013/10/22)
-
- Copper-catalyzed synthesis of alkylphosphonates from H-phosphonates and N-tosylhydrazones
-
A new catalytic system for the alkylation of H-phosphonates and diphenylphosphine oxide with N-tosylhydrazones has been developed. In the presence of copper(I) iodide and base, H-phosphonates react with N-tosylhydrazones to afford the corresponding coupled alkylphosphonates in good to excellent yields without any ligands. Alkylphosphonates can also be prepared in a one-pot process directly from carbonyl compounds without the isolation of tosylhydrazone intermediates.
- Miao, Wenjun,Gao, Yuzhen,Li, Xueqin,Gao, Yuxing,Tang, Guo,Zhao, Yufen
-
p. 2659 - 2664
(2013/01/15)
-
- Synthesis and characterization of 1,8-naphthalimide with [6]helicene skeleton
-
A 1,8-naphthalimide with [6]helicene derivative scaffold has been designed and synthesized. The (P)- and (M)-enantiomers of the [6]helicene derivative were resolved by HPLC on a chiral column. The single crystal of the [6]helicene derivative exhibits an intermolecular interactions of the 1,8-naphthalimide units. The Royal Society of Chemistry 2012.
- Kogiso, Toshitaka,Yamamoto, Kosuke,Suemune, Hiroshi,Usui, Kazuteru
-
supporting information; experimental part
p. 2934 - 2936
(2012/05/07)
-
- Photoinduced energy and electron transfer in phenylethynyl-bridged zinc porphyrin-oligothienylenevinylene-C60 ensembles
-
Donor-bridge-acceptor triad (Por-2TV-C60) and tetrad molecules ((Por)2-2TV-C60), which incorporated C60 and one or two porphyrin molecules that were covalently linked through a phenylethynyl-oligothienylenevinyl
- Urbani, Maxence,Ohkubo, Kei,Islam, D. M. Shafiqul,Fukuzumi, Shunichi,Langa, Fernando
-
supporting information; experimental part
p. 7473 - 7485
(2012/07/28)
-
- Synthesis of α-arylphosphonates using copper-catalyzed α-arylation and deacylative α-arylation of β-ketophosphonates
-
Efficient methods for the direct arylation and deacylative arylation of β-ketophosphonates with iodoarenes in presence of a copper(I) or a copper(II) salt as the catalysts have been developed. The corresponding α-arylphosphonates were obtained in high yields. A tentative mechanism for the deacylative arylation reaction was proposed on the basis of the experimental data. Copyright
- Rout, Laxmidhar,Regati, Sridhar,Zhao, Cong-Gui
-
experimental part
p. 3340 - 3346
(2012/01/17)
-
- Synthesis of p-Quinquephenyl from E,E-1,4-Bis(4-bromophenyl)-1,3-butadiene
-
p-Quinquephenyl was synthesized in five steps from E,E-1,4-bis(4- bromophenyl)-1,3-butadiene in 34% overall yield. The butadiene was prepared in six steps from 4-bromobenzaldehyde in 35% overall yield. Copyright Taylor & Francis Group, LLC.
- Davis, Matthew C.,Groshens, Thomas J.
-
experimental part
p. 206 - 218
(2011/03/18)
-
- AMYLOID BINDING AGENTS
-
There are provided compounds and methods for the detection of amyloids and treatment of diseases related to amyloids including Alzheimer?s disease and other related amyloid-based neurodegenerative diseases
- -
-
Page/Page column 38-39; 42
(2011/06/26)
-
- Synthesis, UV/vis spectra and electrochemical characterisation of arylthio and styryl substituted ferrocenes
-
Two series of substituted ferrocenes were synthesised using either the Horner-Wadswor th-Emmons reaction or monolithiation of ferrocene. The series consist of arylthio- and styryl-ferrocenes with different substituents in the para position of the aryl rings of the systems. The electronic communication was investigated by comparing the substituent effects in absorption spectroscopy and in cyclic voltammetry. A small substituent effect was found in the electronic transitions of the styryl substituted ferrocenes. The oxidation of the ferrocene derivatives showed clear substituent effects as illustrated by the linear Hammett plots. The effect was shown to be an order of magnitude larger in the arylthio-systems than in the styryl systems. It is suggested that the reason behind the large effect is a direct sulfur-iron orbital overlap. Versita Sp. z o.o.
- Sorensen, Thomas J.,Nielsen, Merete F.
-
experimental part
p. 610 - 618
(2012/04/10)
-
- Preparation of benzylphosphonates via a palladium(0)-catalyzed cross-coupling of H-phosphonate diesters with benzyl halides. Synthetic and mechanistic studies
-
We have developed a new, efficient method for the synthesis of benzylphosphonate and benzylphosphonothioate diesters via a palladium(0)- catalyzed cross-coupling reaction between benzyl halides and H-phosphonate or H-phosphonothioate diesters, using Pd2(dba)3(CHCl 3) as a palladium source and Xantphos as a supporting ligand. Some mechanistic aspects of these reactions were investigated using 31P NMR spectroscopy.
- Laven, Gaston,Kalek, Marcin,Jezowska, Martina,Stawinski, Jacek
-
experimental part
p. 967 - 975
(2010/08/04)
-
- Rational design of amyloid binding agents based on the molecular rotor motif
-
New fluorescent probes, designed based on the molecular rotor motif, displayed good affinity for aggregated b-amyloid peptides. The physical and fluorescence properties of these probes can be fine tuned by modifying their chemical structures. These findin
- Sutharsan, Jeyanthy,Dakanali, Marianna,Capule, Christina C.,Haidekker, Mark A.,Yang, Jerry,Theodorakis, Emmanuel A.
-
scheme or table
p. 56 - 60
(2010/11/02)
-
- Synthesis and evaluation of stilbene derivatives as a potential imaging agent of amyloid plaques
-
Fluorescence probes that can detect Aβ (β-amyloid peptide) plaque are important tools for diagnosis of Alzheimer's disease (AD), and 4-N-methylamino-4′-hydroxystilbene (SB-13) is one of the promising candidate molecules. We report here the synthesis of SB-13 derivatives that consist of various electron donating/withdrawing moieties and distinct size of N-substituents. The synthesized compounds were screened for detection of Aβ40 fibrils in vitro. Four compounds exhibited more than sixfold intensity increase, and they were further analyzed for detail bindings and Aβ plaque imaging. Among these molecules, compound 42 meets two critical requirements for imaging agent; high fluorescence responsiveness and strong binding affinity. This compound showed more than 25-fold increase with the dissociation constant of 1.13 ± 0.37 μM. In AD mouse brain tissue, 42 selectively stained Aβ plaque, more specifically peripheral regions of Aβ plaque. This finding demonstrated its potential use as brain-imaging agents for AD studies.
- Hong, Myeng Chan,Kim, Yun Kyung,Choi, Jae Yong,Yang, Si Qiang,Rhee, Hakjune,Ryu, Young Hoon,Choi, Tae Hyun,Cheon, Gi Jeong,An, Gwang Il,Kim, Hye Yun,Kim, Youngsoo,Kim, Dong Jin,Lee, Jun-Seok,Chang, Young-Tae,Lee, Kyo Chul
-
experimental part
p. 7724 - 7730
(2011/01/13)
-
- Synthesis and photo-physical properties of methoxy-substituted π-conjugated-2,2′-bipyridines
-
4,4′-Bis-vinyl-2,2′ bipyridines have been known in the area of materials chemistry since last few decades. Bipyridine molecules bearing donor substituents in their π backbone are examples of 'push-pull' molecules. Emissive properties of such ligands depen
- Chatterjee, Tanmay,Sarma, Monima,Das, Samar K.
-
supporting information; scheme or table
p. 1985 - 1988
(2010/06/21)
-
- NOVEL THIOPHENE-BASED DYE AND PREPARATION THEREOF
-
The present invention relates to a thiophene-based dye and a preparation thereof, and more particularly, to dye compounds, which are used for a dye-sensitized solar cell (DSSC), and provides better molar extinction coefficient, JSc (short-circuit photocurrent density) and photoelectric conversion efficiency than a conventional dye to enhance efficiency of a solar cell.
- -
-
Page/Page column 64-65; 70-72
(2009/05/28)
-
- [1]BENZOTHIENO[3,2-B][1]BENZOTHIOPHENE COMPOUND AND METHOD FOR PRODUCING THE SAME, AND ORGANIC ELECTRONIC DEVICE USING THE SAME
-
A [1]benzothieno[3,2-b][1]benzothiophene compound expressed by General Formula (I): General Formula (I) where X and Y are each independently a hydrogen atom; a halogen atom; or a functional group having a straight or branched aliphatic alkyl group optionally having a halogen atom, a functional group having an alicyclic alkyl group optionally having a halogen atom, a functional group having a straight or branched aliphatic alkenyl group optionally having a halogen atom, a functional group having an alicyclic alkenyl group optionally having a halogen atom, a functional group having a carboxyl group, or a functional group having a thiol group, as a partial structure; and X and Y are the same or each independently different, provided that at least one of X and Y has a straight or branched aliphatic alkenyl group, an alicyclic alkenyl group, a carboxyl group or a thiol group, as a partial structure.
- -
-
Page/Page column 40
(2009/12/02)
-
- Two-photon absorbing materials with quenched emission
-
The present invention provides substituted phenanthroline compounds with high two photon absorption cross sections, as well as substituted phenanthroline compounds which additionally have quenched fluorescence emission upon two photon absorption.
- -
-
Page/Page column 6
(2009/01/20)
-
- ASYMMETRIC STYRYL DERIVATIVES AND ORGANIC LIGHT EMITTING DIODE PREPARED USING THE SAME
-
Disclosed are asymmetric styryl derivatives and an organic light emitting diode prepared using the same. More particularly, there are provided asymmetric styryl derivatives that can provide a blue organic light emitting diode with superior thermal stability, as well as improved luminous efficiency, improved brightness, and extended lifetime, by synthesizing a novel thermally stable compound with a styryl structure represented by Formula 1, and using the compound as a dopant in an organic light emitting layer (EML) of a multilayered organic light emitting diode, and an organic light emitting diode prepared by the same.
- -
-
Page/Page column 12
(2008/12/07)
-
- NOBLE RUTHENIUM-TYPE SENSITIZERS AND METHOD OF PREPARING THE SAME
-
The present invention relates to a noble ruthenium-type dye and a making method thereof, and more particularly, to a noble ruthenium- type dye(sensitizer) which is used to manufacture a dye-sensitized solar cell, drastically improves a photoelectric conve
- -
-
Page/Page column 27; 30
(2008/12/08)
-
- SUBSTITUTED AROMATIC COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES
-
The invention relates to compounds of structural formula (I): Formula (I), or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein Y, L, A, W1, W2, and R'1 are defined herein. These compounds
- -
-
Page/Page column 76
(2010/11/28)
-