Easy access to drug building-blocks through benzylic C-H functionalization of phenolic ethers by photoredox catalysis
A visible light-mediated photocatalyzed C-C-bond forming method for the benzylic C-H functionalization of phenolether containing synthetic building blocks based on a radical-cation/deprotonation strategy is reported. This method allows the mild, selective generation of benzyl radicals in phenolic complex molecules and drug-like compounds, providing new entries in synthetic and medicinal chemistry.
Brandhofer, Tobias,Derdau, Volker,García Manche?o, Olga,Méndez, María,P?verlein, Christoph,Stinglhamer, Martin
supporting information
p. 6756 - 6759
(2021/07/13)
The transformation of dihydroxyphenylalanine (DOPA) to metal uptake systems and ionophores
The crafting of DOPA to metal uptake systems and ionophores, by attachment of ligands to the hydroxyl groups, is illustrated.
Ranganathan, Subramania,Tamilarasu, Natarajan
p. 727 - 731
(2007/10/03)
Process for producing threo-3-(3,4-dihydroxyphenyl)serine
Racemic or optically active threo-3-(3,4-dihydroxyphenyl)serine can be readily produced via a few short steps by a process involving the steps of reacting a racemic or optically active N-acyl DOPA derivative represented by the formula ?I!: STR1 wherein X
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(2008/06/13)
Synthesis of 3,4-dihydro- and 1,2,3,4-tetrahydroisoquinolines
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Ishida,Fujii,Nakamura,et al.
p. 1994 - 2006
(2007/10/02)
L-αmethyldopa and L-dopa ribosides and derivatives
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Chavis,Grodenic,Imbach
p. 219 - 227
(2007/10/02)
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