cas 400744-57-2, 5-(3-METHYLPHENYL)-2-FUROIC ACID | Articles data ｜lookchem

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400744-57-2

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Shedding X-ray Light on the Role of Magnesium in the Activity of Mycobacterium tuberculosis Salicylate Synthase (MbtI) for Drug Design
The Mg2+-dependent Mycobacterium tuberculosis salicylate synthase (MbtI) is a key enzyme involved in the biosynthesis of siderophores. Because iron is essential for the survival and pathogenicity of the microorganism, this protein constitutes an attractiv
Mori, Matteo,Stelitano, Giovanni,Gelain, Arianna,Pini, Elena,Chiarelli, Laurent R.,Sammartino, José C.,Poli, Giulio,Tuccinardi, Tiziano,Beretta, Giangiacomo,Porta, Alessio,Bellinzoni, Marco,Villa, Stefania,Meneghetti, Fiorella
p. 7066 - 7080
(2020/07/28)

Design, synthesis, and electrophysiological evaluation of NS6740 derivatives: Exploration of the structure-activity relationship for alpha7 nicotinic acetylcholine receptor silent activation
The α7 nicotinic acetylcholine receptor (nAChR) silent agonists, able to induce receptor desensitization and promote the α7 metabotropic function, are emerging as new promising therapeutic anti-inflammatory agents. Herein, we report the structure–activity
Pismataro, Maria Chiara,Horenstein, Nicole A.,Stokes, Clare,Quadri, Marta,De Amici, Marco,Papke, Roger L.,Dallanoce, Clelia
(2020/08/19)

PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS
Provided herein are non-peptide GLP-1 receptor modulator compounds, for example, of Formula I, pharmaceutical compositions comprising such compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of a metab
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(2012/01/14)

Discovery of new C3aR ligands. Part 1: Arginine derivatives
The synthesis and in vitro binding of several new arginine-containing C3aR ligands are reported. DMPK properties and functional activities of selected compounds have been evaluated. One compound is shown to be active in an in vivo model of airway inflamma
Denonne, Frederic,Binet, Sophie,Burton, Maggi,Collart, Philippe,Dipesa, Alan,Ganguly, Tanmoy,Giannaras, Alexander,Kumar, Seema,Lewis, Timothy,Maounis, Florence,Nicolas, Jean-Marie,Mansley, Tamsin,Pasau, Patrick,Preda, Dorin,Stebbins, Karin,Volosov, Alexander,Zou, Dong
p. 3258 - 3261
(2008/02/08)

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Chemical Properties

Boiling Point: 368.3 °C at 760 mmHg
Flash Point:176.6 °C
Density: 1.215 g/cm³
Vapor Pressure: 4.48E-06mmHg at 25°C
Refractive Index: 1.574
PSA: 50.44000
LogP: 2.95320

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