- Reaction-based fluorescent turn-on probe for selective detection of thiophenols in aqueous solution and living cells
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A novel turn-on florescent probe based on a nucleophilic substitution reaction was developed for the detection of thiophenols in aqueous solution and in living cells. In this probe, 10-hydroxyl derivative of coumarin 6H was selected as fluorophore, 2, 4-dinitrophenlate moiety acted simultaneously as recognition unit and fluorophore quencher. This probe features a remarkable large Stokes shift (128?nm) and shows a highly selective detection process for thiophenols with significant fluorescence turn-on response. Notably, biothiols, aliphatic thiols, amino acids and reducing anions do not interfere with the sensing of thiophenols. The probe shows good linearity ranges with low detection limit of 36?nM for thiophenols. More importantly, it was successfully applied for practical detection of thiophenols in real water samples with a good recovery and imaging of thiophenols in living cells, demonstrating its practical application in environmental samples and biological systems.
- Wang, Xiao-Bo,Hao, Xue,Zhang, Datong,Jiang, Yan
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- Simultaneous Visualization of Endogenous Homocysteine, Cysteine, Glutathione, and their Transformation through Different Fluorescence Channels
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Studying numerous biologically important species simultaneously is crucial to understanding cellular functions and the root causes of related diseases. Direct visualization of endogenous biothiols in biological systems is of great value to understanding their biological roles. Herein, a novel multi-signal fluorescent probe was rationally designed and exploited for the simultaneous sensing of homocysteine (Hcy), cysteine (Cys), and glutathione (GSH) using different emission channels. This probe was successfully applied to the simultaneous discrimination between and visualization of endogenous Hcy, Cys, GSH, and their transformation in living cells.
- Yin, Guoxing,Niu, Tingting,Yu, Ting,Gan, Yabing,Sun, Xinyu,Yin, Peng,Chen, Haimin,Zhang, Youyu,Li, Haitao,Yao, Shouzhuo
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- Synthesis of a NIR fluorescent dye and its application for rapid detection of HSO3? in living cells
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SO2 and its derivatives (HSO3?, SO32?) play a significant important role in many industries and organisms. Based on coumarin and benzopyranose, a promising NIR ratiometric fluorescent probe BAOA (11-oxo-2,2′,3,3′,6,7,7′,8′-octahydro -1H,1′H,5H,6′H,11H- [10,12′-bipyrano [2,3-f] pyrido [3,2,1-ij] quinolin]-13′-ium perchlorate) was designed and developed to detect HSO3? rapidly and sensitively. The sensing mechanism was Michael addition reaction, in which, strongly nucleophilic HSO3? attacked carbon-carbon double bonds and BAOA-HSO3 was formed. A superior linear calibration curve between the fluorescence ratio I490/I722 and concentrations of HSO3? was obtained in the range of 1.25–8.75 μmol/L and the LOD was figured out as 63.0 nmol/L. Cell experiments showed that BAOA could not only locate mitochondria, lysosomes, ER and Golgi but also detect exogenous HSO3? in living cells.
- Bu, Dandan,Li, Zhanxian,Ren, Haohui,Yu, Mingming,Zhang, Hongyan,Zhang, Qiang
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- A novel colorimetric and ratiometric fluorescent probe for selective detection of bisulfite in real samples and living cells
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An abnormal level of bisulfite can induce toxicological effects associated with lung cancer, cardiovascular and neurological disorders. Therefore, it is of significance to develop an effective fluorescent probe to detect bisulfite in living cells. Herein, a novel fluorescent probe QPCT, based on a 1,4-addition mechanism, was constructed for the colorimetric and ratiometric detection of bisulfite. QPCT displayed high selectivity and anti-interference ability to bisulfite over other anions and biothiols. The probe renders a sensitive ratiometric response to bisulfite with a remarkable fluorescence blue shift from 590 to 537 nm and the fluorescence ratio was linear with bisulfite concentration over the range of 0–120 μM. More importantly, QPCT has been successfully applied to detect bisulfite in sugars and living A549 cells, which indicated that QPCT had a great capability for monitoring bisulfite in complex systems.
- Li, Jin,Gao, Ying,Guo, Haoran,Li, Xiaokang,Tang, Haoyang,Li, Jian,Guo, Yuan
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- Extensive reduction in back electron transfer in twisted intramolecular charge-transfer (TICT) coumarin-dye-sensitized TiO2 nanoparticles/film: A femtosecond transient absorption study
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We report the synthesis, characterization, and optical and electrochemical properties of two structurally similar coumarin dyes (C1 and C2). These dyes have been deployed as sensitizers in TiO2 nanoparticles and thin films, and the effect of molecular structure on interfacial electron-transfer dynamics has been studied. Steady-state optical absorption, emission, and time-resolved emission studies on both C1 and C2, varying the polarity of the solvent and the solution pH, suggest that both photoexcited dyes exist in a locally excited (LE) state in solvents of low polarity. In highly polar solvents, however, C1 exists in an intramolecular charge-transfer (ICT) state, whereas C2 exists in both ICT and twisted intramolecular charge-transfer (TICT) states, their populations depending on the degree of polarity of the solvent and the pH of the solution. We have employed femtosecond transient absorption spectroscopy to monitor the charge-transfer dynamics in C1- and C2-sensitized TiO2 nanoparticles and thin films. Electron injection has been confirmed by direct detection of electrons in the conduction band of TiO 2 nanoparticles and of radical cations of the dyes in the visible and near-IR regions of the transient absorption spectra. Electron injection in both the C1/TiO2 and C2/TiO2 systems has been found to be pulse-width limited (2 system than in the C1/TiO2 system. The involvement of TICT states in C2 is solely responsible for the higher electron injection yield as well as the slower BET process compared to those in the C1/TiO2 system. Further pH-dependent experiments on C1- and C2-sensitized TiO2 thin films have corroborated the participation of the TICT state in the slower BET process in the C2/TiO2 system.
- Debnath, Tushar,Maity, Partha,Lobo, Hyacintha,Singh, Balvant,Shankarling, Ganapati S.,Ghosh, Hirendra N.
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- (7-Dialkylamino-3-coumarinyl)pyrazolines – new effective push-pull photogenerators of acidity
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(7-Dialkylamino-3-coumarinyl)pyrazolines and their julolidine analog have been synthesized and proved as new effective photogenerators of acidity. Having D-π-linker ?A conjugated system of push-pull type these compounds possess intensive absorption in visible region of electronic spectra, high photosensitivity and undergo photodehydrogenation with proton elimination in the presence of CCl4 or C2Cl6 with a high speed.
- Traven,Cheptsov,Vershinina,Solovjeva,Chibisova,Dolotov,Ivanov
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- Synthesis method of long-wavelength asymmetric rhodamine dye
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The invention discloses a synthesis method of long-wavelength asymmetric rhodamine. The preparation method of the fluorescent dye comprises the following steps of: firstly, carrying out two-step reaction on 3-aminophenol to obtain a dye intermediate, then carrying out reaction on the obtained intermediate and 1, 6-naphthalene diphenol, and finally carrying out esterification to obtain a target product, namely the long-wavelength asymmetric rhodamine fluorescent dye. Compared with the existing fluorescent dye, the synthesized fluorescent dye has the characteristics of near-infrared emission spectrum, laser wavelength of more than 650 nm, good laser conversion efficiency and the like, the synthesis method is simple to operate and high in yield, and the synthesized fluorescent dye can be applied to the fields of laser, electroluminescence, fluorescent probes and the like.
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Paragraph 0010
(2021/07/08)
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- Near-infrared fluorescent probe for detecting hydrogen sulfide as well as preparation method and application of near-infrared fluorescent probe
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The invention belongs to the technical field of organic synthesis, and particularly relates to a near-infrared fluorescent probe for detecting hydrogen sulfide as well as a preparation method and an application of the near-infrared fluorescent probe. The molecular formula of the fluorescent probe is C42H30N2O5S2, and the structural formula of the fluorescent probe is shown in the specification. The disulfide bond of the fluorescent probe reacts with H2S to break the bond, the sulfydryl of the broken disulfide bond attacks carbonyl in a nucleophilic manner, a rhodamine dye molecular monomer is released, and the fluorescence intensity is enhanced by nearly 10 times and is accompanied by obvious color change, so that the fluorescent probe is relatively rapid in H2S atopic recognition reaction, good in selectivity and relatively high in sensitivity, and the detection limit reaches 7.161*10 M.
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Paragraph 0041-0046
(2021/06/12)
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- Stress response decay with aging visualized using a dual-channel logic-based fluorescent probe
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Diagnosing aging for preventative intervention generally relies on the tracking of aging biomarkers in the resting state. However, the static marker levels are insufficient to fully evaluate aging, particularly given that the stress response capacity (SRC) decay is currently viewed as a critical feature of aging. Therefore, we have developed a dual-channel fluorescent probe ROKS capable of the logic-based visualization of thiophenol (stressor) and HOCl (thiophenol-activated stress response product) in vivo, which provides a new strategy from the time dimension to precisely assess the SRC of individuals under stress using the dual-channel fluorescence ratio. Using ROKS we observed that the SRC of live cells decayed with senescence, and that a higher SRC was found for young vs. aged Caenorhabditis elegans. As such, our study offers a promising strategy for the fluorescence-guided diagnosis of aging and paves the way for accurate evaluation of the efficacy of anti-aging drugs.
- Guo, Yuan,James, Tony D.,Li, Jian,Li, Xiaokang,Li, Xinming,Shi, Donglei,Teng, Hao,Tian, Jingye,Zhang, Yanhui
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p. 13483 - 13491
(2021/11/01)
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- A general strategy for selective detection of hypochlorous acid based on triazolopyridine formation
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Triazolopyridines are an important kind of fused-ring compounds. A HOCl-promoted triazolopyridine formation strategy is reported here for the first time in which hypochlorous acid (HOCl) mildly and efficiently promotes the formation of 1,2,4-triazolo[4,3-a]pyridines NT1-NT6 from various 2-pyridylhydrazones N1-N6. N6, a rhodol-pyridylhydrazone hybrid, was developed into a fluorescent probe for the selective detection of HOCl, and successfully applied to probe endogenous HOCl in living cells and zebrafish in situ and in real time. The present intramolecular cyclization reaction is selective and atom-economical, thereby not only providing an important approach for the convenient synthesis of triazolopyridines, but also offering a general strategy for sensitive, selective and biocompatible detection of endogenous HOCl in complex biosystems.
- Zhang, Yanhui,Teng, Hao,Gao, Ying,Afzal, Muhammad Wasim,Tian, Jingye,Chen, Xi,Tang, Haoyang,James, Tony D.,Guo, Yuan
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supporting information
p. 2917 - 2920
(2020/03/13)
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- Rhodol-HBT derivative and preparation method and application thereof
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The invention discloses a Rhodol derivative as shown in a structural general formula (I). According to the invention, benzothiazole is introduced into a Rhodol structure, a novel Rhodol-HBT dye is developed, the dye has multiple excellent properties of two fluorophores Rhodol and HBT, and two active sites which are easy to modify are provided. The compound can be used as a fluorescent probe for logic detection of thiophenol and hypochlorous acid, visual imaging of the oxidative stress process in cells, zebra fishes and nematodes is successfully achieved by means of a fluorescence confocal microscope, and dynamic evaluation of aging of the cells and the nematodes is further achieved by means of the probe.
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Paragraph 0019
(2020/09/16)
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- Synthesis and properties of seminaphthorhodafluor red laser dyes
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In the present work, we synthesized two seminaphthorhodafluor red laser dyes SNARF-X1 and SNARF-X2 and investigated their photo-physical properties in different solvents and the laser properties in ethanol. It was found that the wavelengths of absorption and fluorescence emission spectra are not very sensitive to the solvent polarity, while the fluorescence intensities decrease with the increase in solvent polarity. SNARF-X1 and SNARF-X2 not only emit tunable red laser (590–670?nm for SNARF-X1 and 600–680?nm for SNARF-X2) but also show high laser conversion efficiency. The above two dyes also show high photo-stability under 532?nm ND:YAG laser irradiation. In this regard, the half-lives of laser efficiency for SNARF-X1 and SNARF-X2 are 7?h and 6?h, respectively.
- Ming, Wei,Hu, Xiaojie,Zhang, Zhizhong,Chang, Shunzhou,Chen, Risheng,Tian, Baozhu,Zhang, Jinlong
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p. 1991 - 2002
(2020/01/11)
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- COUMARIN-MODIFIED ANDROGENS FOR THE TREATMENT OF PROSTATE CANCER
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Provided are androstane and dihydrotestosterone compounds functionalized with carbocyclic groups or heterocyclic groups that may be saturated or unsaturated. The compounds may be used in methods of inhibiting cell growth of malignant cells and/or hyperplastic cells and/or treating individuals having diseases associated with malignant cell growth (e.g., cancer, such as, for example, prostate cancer) and/or hyperplastic cell growth and/or molecular imaging of malignant cells and/or hyperplastic cells and/or inducing degradation of a target protein. Also provided are compositions.
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Paragraph 0114
(2020/11/12)
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- Near-infrared fluorescent probe for simultaneously detecting DNA and RNA under double channels as well as preparation method and application of the near-infrared fluorescent probe
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The invention discloses a fluorescent probe for simultaneously detecting DNA and RNA in cells under double channels as well as a preparation method and application of the fluorescent probe. The structure of the fluorescent probe is shown as a formula (I) or (II), wherein the Ar is an aromatic ring or an aromatic heterocyclic ring; the R1 and R2 are respectively and independently hydrogen, N-piperazine, N-methyl piperazine, -NH(CH2)nR3 and -NR3R4; the n is any integer from 1 to 5, and R3 and R4 are respectively and independently hydrogen, C1-C5 alkyl or C1-C5 haloalkyl; the A- is halide ions orp-toluenesulfonic acid ions. The fluorescent probe disclosed by the invention can be used for simultaneously detecting DNA and RNA in vitro and in cells under double channels; meanwhile, the fluorescent probe has the characteristics of rapid synthesis, near-infrared emission wavelength, good light stability, high detection sensitivity and the like, and is convenient to popularize and apply.
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Paragraph 0056-0057; 0061
(2020/05/30)
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- Method for synthesizing 8-hydroxyjulolidine
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The invention relates to a method for synthesizing 8-hydroxyjulolidine. The method comprises the following steps: reacting 3-methoxyaniline, X-(CH2)3-Y and an inorganic base under a heating condition,separating water during the reaction, and carrying out post-treatment after the completion of the reaction to obtain crude 8-hydroxyjulolidine; mixing the crude 8-hydroxyjulolidine with a halogen acid, heating the obtained mixture to react the mixture, and cooling and filtering the obtained solution after the reaction is completed in order to obtain a halogen acid salt of 8-hydroxyjulolidine; andmixing the halogen acid salt of 8-hydroxyjulolidine with water, neutralizing the obtained solution with a base, and carrying out extraction, drying, reduced pressure concentrating, beating and purification to obtain the 8-hydroxyjulolidine. The method has the advantages of abandoning of traditional column chromatography purification, suitableness for industrial production, and high yield.
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- Endoplasmic reticulum targeted fluorescent probe for the detection of hydrogen sulfide based on a twist-blockage strategy
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Hydrogen sulfide (H2S) is very important for humans and is involved in many physiological processes. Here, we designed and reported a new naked-eye colorimetric fluorescent probe Z1 for detecting H2S in absolute HEPES solution. The fluorescence intensity, after the reaction of the probe and H2S, is about 32 times that of the probe alone. When the concentration of H2S is 0-100 μM, the detection limit (DL) is rather low at about 0.15 μM (3σ/slope). The response mechanism is based on the leaving of the 2,4-dinitrobenzene moiety, followed by intramolecular cyclization to give a fluorescent iminocoumarin-benzothiazole group. Moreover, Z1 was applied to endogenous and exogenous H2S imaging in living cells. The high overlap coefficient proved that probe Z1 has good ER-tracker localization in living cells.
- Zhang, Yongru,Zhang, Beibei,Li, Zipeng,Wang, Lianbang,Ren, Xueling,Ye, Yong
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supporting information
p. 8778 - 8783
(2019/10/16)
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- Compounds and Method for Imaging Cancer
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A compound, a method of imaging a cell, and a method of detecting a cancer, an inflammatory disease, or a neoplastic disease are provided. The compound includes a nitroxide derivative of a fluorophore that is activatable upon exposure to free radicals. The method of imaging a cell includes contacting the cell with an activatable nitroxide derivative of a fluorophore. The method of detecting a cancer, an inflammatory disease, or a neoplastic disease includes administering an activatable nitroxide derivative of a fluorophore and then imaging one or more cells contacted with the compound.
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- Effect of Structure on the Spin-Spin Interactions of Tethered Dicyanomethyl Diradicals
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Stable organic radicals with switchable spin states have attracted attention for a variety of applications, but a fundamental understanding of how radical structure effects the weak bonding interactions between organic radicals is limited. To evaluate the effect of chemical structure on the strength and nature of such spin interactions, a series of 14 tethered aryl dicyanomethyl diradicals were synthesized, and the structure and thermodynamic properties of the diradicals were investigated. These studies indicate that the nature of the dimer and the equilibrium thermodynamic parameters of the diradical-dimer equilibria are highly sensitive to the attachment point of the linker, the length of the linker, and the substituents on the radical itself. Values of the intramolecular Ka vary from as small as 5 to as high as 105 depending on these variables. An X-ray crystal structure for a linked ortho-substituted diradical shows that the diradical forms an intramolecular sigma dimer in the crystalline state with an elongated C-C bond (1.637 ?). Subtle changes to the radical structure influences the nature of the spin interactions, as fixing the dimethylamino substituent on the radical into a ring to make a julolidine-derived diradical leads to the weakest bonding interaction observed (ΔGbonding = 1 kcal mol-1) and changes the spin-paired species from a sigma dimer to a diradical pimer. This work has implications for the design of stimuli-responsive materials that can reversibly switch between the dramatically different properties of closed-shell species and the unique properties of diradicals.
- Zhang, Rui,Peterson, Joshua P.,Fischer, Logan J.,Ellern, Arkady,Winter, Arthur H.
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supporting information
p. 14308 - 14313
(2018/10/24)
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- A examination jing fluorescence probe and its application (by machine translation)
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The invention provides a fluorescent probe for examination jing, its chemical name is 9 - chloro - 11 - oxo - 2, 3, 6, 7, - tetrahydropyran [2, 3, f] pyrrolo [3, 2, 1 - ij] quinoline - 10 - formaldehyde. The fluorescent probe synthesis method, first synthetic 8 - hydroxy long lourie decides, then synthesis of 9 - hydroxy - 2, 3, 6, 7, - tetrahydropyran [2, 3, f] pyrrolo [3, 2, 1 - ij] quinoline - 11 - ketone, the final synthetic fluorescent probe. The above fluorescent probe in the detection solution content of the jing the excitation wavelength is 480 nm, emission wavelength of 560 nm; detection time is added to the fluorescent probe 2 min after. Fluorescent probe of this invention Hy - N2 H4 Simple synthesis steps, high yield, simple separation and purification steps; and in aqueous solution can be performed in concentration determination, determining mild condition; rapid reaction of hydrazine, the specificity is good, high sensitivity. (by machine translation)
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Paragraph 0023; 0024
(2018/04/26)
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- Rhodamine fluorescence dye and preparation method thereof
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The invention discloses a rhodamine fluorescence dye and a preparation method thereof. A classic rhodamine synthesis method is used as a basis, chemical groups having different functions are introduced to a rhodamine parent through reasonable structural modification, a conjugative effect is added, and hyperchromic groups, such as hydroxy, diethylin and azabicyalo, are changed. The prepared novel rhodamine fluorescence dye has a larger emission wavelength and higher light quantum yield and also has more reaction loci, so that follow-up reaction is more convenient. In addition, the rhodamine fluorescence dye has appropriate Stokes shift, and wavelength interference excitation can be avoided in follow-up fluorescence detection, so that analysis results are more accurate.
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Paragraph 0070; 0071; 0072; 0073
(2017/10/06)
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- Novel Iminocoumarin Derivatives: Synthesis, Spectroscopic and Computational Studies
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Three novel iminocoumarin derivatives with high quantum yield are synthesized from 3-benzimidazole substituted coumarin and different aromatic aldehydes. The photophysical behavior of the synthesized compounds was studied using UV-visible and fluorescence spectroscopy in polar and non-polar solvents. The compounds show absorption maxima at around 450 nm and emission maxima at around 500 nm. The quantum yields of compounds in dichloromethane and chloroform are more than 0.90. The absorption, emission and quantum yield of compounds are dependent on the polarity of solvents. Along with an intense absorption, these compounds show shoulder absorption peak in the studied solvents. The solvent polarity plots revealed the charge transfer process in the synthesized molecules from donor to acceptor. Density Functional Theory and Time Dependent Density Functional Theory computations have been used to have more understanding of the structural, molecular, electronic and photophysical parameters of the dyes. The dyes were characterized by FT-IR, 1H NMR, 13C NMR and mass spectral analysis.
- Chemate, Santosh B.,Sekar, Nagaiyan
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p. 1615 - 1628
(2015/11/24)
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- A fluorescent probe for H2S in vivo with fast response and high sensitivity
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In this work, we design and synthesize a new near-infrared (NIR) ratiometric fluorescent probe FD-H2S for the highly sensitive (DL 68.2 nM) detection of H2S with fast response (15 s), large emission shift (220 nm) and excellent enhancement (168-fold in ratiometric value). The probe could be applied for monitoring and imaging of exogenous or endogenous H2S in live MCF-7 cells and in live mice with the fastest response.
- Li,Yao,Fan,Jiang,Wang,Xia,Peng
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supporting information
p. 16225 - 16228
(2015/11/16)
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- Lighting up fluoride ions in cellular mitochondria using a highly selective and sensitive fluorescent probe
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We report a highly selective and sensitive fluorescent probe (FP) for detecting fluoride ions, for the first time, lighting up the fluoride ions in mitochondria with a strong green fluorescence. FP could be easily prepared as fluoride paper test strips to detect fluoride ions in aqueous solutions with a detection limit as low as 19 ppb.
- Zhang, Shiling,Fan, Jiangli,Zhang, Shuangzhe,Wang, Jingyun,Wang, Xianwu,Du, Jianjun,Peng, Xiaojun
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supporting information
p. 14021 - 14024
(2015/02/19)
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- Rational design and efficient synthesis of a fluorescent-labeled jasmonate
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A fluorescent-labeled jasmonate was rationally designed based on examination of the model of interaction between the jasmonate and its receptor. An efficient synthetic route has been developed for this molecule. The biological activity of this fluorescent probe was retained which was similar to that of the methyl jasmonate as examined by root growth inhibition bioassay. This fluorescent probe will greatly facilitate biological studies of jasmonates through fluorescent imaging.
- Liu, Songbai,Wang, Wu-Hong,Dang, Ya-Li,Fu, Yuanqing,Sang, Ruocheng
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supporting information; experimental part
p. 4235 - 4239
(2012/09/07)
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- Ruthenium(II)-polyimine-coumarin light-harvesting molecular arrays: Design rationale and application for triplet-triplet-annihilation-based upconversion
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RuII-bis-pyridine complexes typically absorb below 450 nm in the UV spectrum and their molar extinction coefficients are only moderate (Iμ-1cm-1). Thus, Ru II-polyimine complexes that show intense visible-light absorptions are of great interest. However, no effective light-harvesting ruthenium(II)/organic chromophore arrays have been reported. Herein, we report the first visible-light-harvesting RuII-coumarin arrays, which absorb at 475 nm (Iμ up to 63300M-1cm-1, 4-fold higher than typical RuII-polyimine complexes). The donor excited state in these arrays is efficiently converted into an acceptor excited state (i.e., efficient energy-transfer) without losses in the phosphorescence quantum yield of the acceptor. Based on steady-state and time-resolved spectroscopy and DFT calculations, we proposed a general rule for the design of Ru II-polypyridine-chromophore light-harvesting arrays, which states that the 1IL energy level of the ligand must be close to the respective energy level of the metal-to-ligand charge-transfer (MLCT) states. Lower energy levels of 1IL/3IL than the corresponding 1MLCT/3MLCT states frustrate the cascade energy-transfer process and, as a result, the harvested light energy cannot be efficiently transferred to the acceptor. We have also demonstrated that the light-harvesting effect can be used to improve the upconversion quantum yield to 15.2% (with 9,10-diphenylanthracene as a triplet-acceptor/annihilator), compared to the parent complex without the coumarin subunit, which showed an upconversion quantum yield of only 0.95%. Copyright
- Wu, Wanhua,Ji, Shaomin,Wu, Wenting,Shao, Jingyin,Guo, Huimin,James, Tony D.,Zhao, Jianzhang
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supporting information; scheme or table
p. 4953 - 4964
(2012/06/04)
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- Development of an ICT-based ratiometric fluorescent hypochlorite probe suitable for living cell imaging
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We have judiciously constructed a novel ICT-based ratiometric OCl - probe capable of ratiometric imaging in the live cells based on the new OCl--promoted de-diaminomaleonitrile reaction. The Royal Society of Chemistry 2011.
- Yuan, Lin,Lin, Weiying,Song, Jizeng,Yang, Yueting
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supporting information; experimental part
p. 12691 - 12693
(2012/01/12)
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- Chemiluminescence of Organic Peroxides: Intramolecular Electron-Exchange Luminescence from a Secondary Perester
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The reaction of an aminocoumarincarboxylic acid chloride (Coumarin 343) with 1-phenethyl hydroperoxide results in light emission that is easily detected with the unaided eye.This reaction proceeds through a secondary perester intermediate.Intramolecular electron exchange, modeled after the analogous process in the bioluminescence of the firefly, is proposed as the mechanism for light generation.Attempts to carry out this reaction under conditions where the coumarin acid is recycled were not successful.
- Gompel, Joseph Van,Schuster, Gary B.
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p. 1465 - 1468
(2007/10/02)
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- Pyrylium dyes having a fused rigidized nitrogen-containing ring
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A class of pyrylium dyes, having at least one rigidized, nitrogen-containing heterocyclic ring fused thereto is described. The rigidized dyes are useful lasing components in lasing media.
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