- Studies on anti-amoebic compounds. Part V. Synthesis of dichloromethanesulphonamides
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Synthesis of a variety of dichloromethanesulphonamides, including a close structural analogue of a well-known drug, namely diloxanide furoate, and their anti-amoebic activities are reported. anti-amoebic compounds / diloxanide furoate / dichloroacetamides / dichloromethanesulphonamides
- Parthasarathy, P C,Ananthan, L,Likhate, M A,Manjunatha, S G,Kalyanam, N
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p. 195 - 199
(2007/10/02)
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- Experiments Concerning the Reduction of Dichloromethanedisulfonyl Dichloride
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Mild reducing agents, including methanol, reduce dichloromethanedisulfonyl dichloride (2) to give dichloro(chlorosulfonyl)methanesulfinic acid (6) which desulfinylates spontaneously to form dichloromethanesulfonyl chloride (9).Chloromethanedisulfonyl dichloride (12) is not reduced under these conditions and can be derivatized "normally", for instance with morpholine.
- Senning, Alexander
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p. 2090 - 2092
(2007/10/02)
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- N-sulfonyl-N-dihalophenylimidazolidinediones
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3-(3' -Dihalophenyl)-1-sulfonylimidazolidine-2,4-5'-diones of the formula: STR1 wherein X is a halogen atom, R1 is a C1 -C12 alkyl group, a C2 -C4 alkenyl group or a halogenated C1 -C4 alkyl group having 1 to 3 halogen atoms, and R2 and R3 are individually a hydrogen atom or a methyl group, which show high microbicidal activities against various fungi and bacteria without any material toxicity to mammals and which plants and can be produced by reacting the corresponding 1-unsubstituted compound with a sulfonyl halide.
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