Modulation of Excess Electron Transfer through LUMO Gradients in DNA Containing Phenanthrenyl Base Surrogates
The modulation of excess electron transfer (EET) within DNA containing a dimethylaminopyrene (C-AP) as an electron donor and 5-bromouracil (BrdU) as an electron acceptor through phenanthrenyl pairs (phen-R) could be achieved by modifying the phenanthrenyl base surrogates with electron withdrawing and donating groups. Arranging the phenanthrenyl units to form a descending LUMO gradient increased the EET efficiency compared to the electron transfer through uniform LUMOs or an ascending LUMO gradient.
Roethlisberger, Pascal,Kaliginediand, Veerabhadrarao,Leumann, Christian J.
Modular functionalization and hydrogel formation: via red-shifted and self-reporting [2+2] cycloadditions
We present a modularly applicable, red-shifted and self-reporting photodynamic covalent crosslinker, abbreviated qStyPy, that performs [2+2] cycloadditions upon irradiation with 470 nm in water. The rational design of qStyPy increases its hydrophilicity due to a permanent charge and features a broad emission in the far-red/near-infrared regime as a readout for the cycloadduct formation, rendering qStyPy suitable for biomedical applications. This journal is
Ludwanowski, Simon,Hoenders, Daniel,Kalayci, Kubra,Frisch, Hendrik,Barner-Kowollik, Christopher,Walther, Andreas