3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS
The present invention relates to 3-azabicyclo[3.1.0]hexane derivatives, which are useful as vanilloid receptor (VR) ligands, methods of treating diseases, conditions and/or disorders modulated by vanilloid receptors with them, and processes for preparing them.
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Page/Page column 53-54
(2009/08/16)
Synthesis of unsymmetrical and regio-defined 2,3,6-quinoxaline and 2,3,7-pyridopyrazine derivatives
Differential reactivity of the amine functionality in a number of common 1,2-diamine starting materials is exploited to undertake an expedient synthesis of unsymmetrical 2,3,6-trisubstituted quinoxaline and unsymmetrical 2,3,7-trisubstituted pyridopyrazin