- Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents
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Sigma receptors (SRs) are recognized as valuable targets for the treatment of neurodegenerative disorders. A series of novel SRs ligands were designed by combining key pharmacophoric amines (i.e., benzylpiperidine or benzylpiperazine) with new 1,3-dithiolane-based heterocycles and their bioisosters. The new compounds exhibited a low nanomolar affinity for sigma-1 and sigma-2 receptors. Five selected compounds were evaluated for their neuroprotective capacity on SH-SY5Y neuroblastoma cell line. They were able to counteract the neurotoxicity induced by rotenone, oligomycin and NMDA. Competition studies with PB212, a S1R antagonist, confirmed the involvement of S1R in neuroprotection from the oxidative stress induced by rotenone. Electrophysiological experiments performed on cortical neurons in culture highlighted the compounds ability to reduce NMDA-evoked currents, suggesting a negative allosteric modulator activity toward the NMDA receptor. Altogether these results qualify our novel dithiolane derivatives as potential agents for fighting neurodegeneration.
- Franchini, Silvia,Linciano, Pasquale,Puja, Giulia,Tait, Annalisa,Borsari, Chiara,Denora, Nunzio,Iacobazzi, Rosa Maria,Brasili, Livio,Sorbi, Claudia
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supporting information
p. 1028 - 1034
(2020/07/21)
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- Design, Synthesis, and Biological Screening of Novel Anthranilic Diamides
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Three series of new anthranilic diamide derivatives containing sulfide, N-cyanomethylsulfilimine, and N-cyanomethylsulfoximine groups were designed and synthesized by combining the active substructures of anthranilic diamides and sulfoxaflor. The structures of all newly synthesized compounds were confirmed by IR and 1H/13C-NMR, and some of them were confirmed by elemental analysis or HRMS too. The synthesized compounds were screened for their insecticidal and fungicidal activities. Bioasssay results indicated that some of the synthesized compounds possessed certain degrees of insecticidal activity against Mythimna separata. However, some compounds exhibited good fungicidal activity against Sclerotinia sclerotiorum.
- Hua, Xuewen,Mao, Wutao,Fan, Zhijin,Ji, Xiaotian,Li, Fengyun,Zong, Guangning,Song, Haibin,Tatiana, Kalinina,Morzherin, Yury Yu.,Belskaya, Nataliya P.,Bakulev, Vasiliy A.
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p. 865 - 875
(2016/05/19)
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- Containing sulfide, N-cyano-sulfur (sulfone) imine structure substituted pyrazole carboxamides double-amide derivatives and process for their preparation and use
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The invention provides a double amide derivative containing a sulfur ether and N-sulfur cyano (sulphone) imine structure and replacing pyrazolecarboxamide and a preparing method and purpose thereof, and relates to double amide derivatives containing the pyrazolecarboxamide. The double amide derivative containing the pyrazolecarboxamide has a chemical structure general formula as shown in the map I. The structure general formula and the synthetic method of the double amide derivative and the purpose for being used as insecticides, antiseptics, a plant virus resistance agent and a plant activator are disclosed. The double amide derivative containing the sulfur ether and N-sulfur cayano (sulphone) imine structure and replacing the pyrazolecarboxamide can be mixed with auxiliaries or synergists which are acceptable in agriculture to form a processing technology to be used for preparing the insecticides, the antiseptics, the plant virus resistance agent and the plant activator. The invention further discloses the purpose and preparing method of the double amide derivative containing the sulfur ether and N-sulfur cyano (sulphone) imine structure and replacing the pyrazolecarboxamide combining with commodity insecticides, commodity antiseptics, commodity plant virus resistance agents and commodity plant activators to be used for preventing and curing plant diseases, insect pests, virus diseases in agriculture, forestry and horticulture.
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Paragraph 0072; 0073-0075
(2016/10/09)
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- Investigation of the catalytic activity of an electron-deficient vanadium(IV) tetraphenylporphyrin: A new, highly efficient and reusable catalyst for ring-opening of epoxides
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In this work, the catalytic activity of high-valent tetraphenylporphyrinatovanadium(IV) trifluoromethanesulfonate, [V IV(TPP)(OTf)2], in the nucleophilic ring-opening of epoxides is reported. This new V(IV) catalyst was used as an efficient catalyst for alcoholysis with primary (methanol, ethanol and n-propanol), secondary (iso-propanol) and tertiary alcohols (tert-butanol), hydrolysis and acetolysis of epoxides with acetic acid and also for the conversion of epoxides to 1,2-diacetates with acetic anhydride, conversion of epoxides to thiiranes with ammonium thiocyanate and thiourea, and for conversion of epoxides to acetonides with acetone. The catalyst was reused several times without loss of its activity.
- Taghavi, S. Abdolmanaf,Moghadam, Majid,Mohammadpoor-Baltork, Iraj,Tangestaninejad, Shahram,Mirkhani, Valiollah,Khosropour, Ahmad Reza,Ahmadi, Venus
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experimental part
p. 2244 - 2252
(2011/10/03)
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- Catalytic conversion of epoxides to 1,3-dioxolanes with phosphomolybdic acid (PMA) in solution and under solvent-free conditions
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The fast and efficient conversion of epoxides into 2,2-dimethyl-1,3- dioxolanes was studied with catalytic amounts of phosphomolybdic acid (PMA) (0.1-0.2 mol %) at room temperature in solution and under solvent-free conditions. The products were obtained in high to excellent yields within 1-2 min. Copyright Taylor & Francis Group, LLC.
- Zeynizadeh, Behzad,Sadighnia, Leila
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experimental part
p. 2274 - 2279
(2009/07/18)
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- Efficient and catalytic conversion of epoxides into 1,3-dioxolanes with LiBF4
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Lithium tetrafluoroborate catalysis the efficient conversion of epoxides with acetone to the corresponding 1,3-dioxolanes in excellent isolated yields. Copyright Taylor & Francis, Inc.
- Kazemi,Kiasat,Ebrahimi
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p. 1441 - 1445
(2007/10/03)
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- Rapid and efficient ring opening of epoxides catalyzed by a new electron deficient tin(IV) porphyrin
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The new electron deficient tin(IV) tetraphenylporphyrinato trifluoromethanesulfonate, [SnIV(tpp)(OTf)2], was used as an efficient catalyst for the alcoholysis, hydrolysis and acetolysis of epoxides. Conversion of epoxides to thiiranes and acetonides were also performed efficiently in the presence of this catalyst.
- Moghadam, Majid,Tangestaninejad, Shahram,Mirkhani, Valiollah,Shaibani, Reza
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p. 6105 - 6111
(2007/10/03)
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- A New Substituted Bis(vic-dioxime) of Its Mono-and Dinuclear Complexes
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9,10-Bis(hydroxyimino)-4,8,11,15-tetra-aza-1,2,17,18-O-di-iso-propylideneoctadecane (H2L) was synthesized by the reaction of 1,2-O-iso-propylidene-4-aza-7-aminoheptane and anti-dichloroglyoxime in ethanol, containing an excess of NaHCO3 as a buffer to neutralize the HCl formed. The mononuclear metal complexes of this ligand have been synthesized with Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) salts. H2L forms mononuclear complexes [(HL)2M] with a metal ligand ratio of 1:2 with M = Co(II) * 2H2O, Ni(II) and Cu(II). Zn(II) and Cd(II) form with H2L complexes [(H2L)(Cl)2M], which have a metal-ligand ratio of 1:1 and a dinuclear complex with UO2(VI). H2L forms the dinuclear complex [(HL)2(OH)2M2] with a metal ligand ratio of 1:1 with M = UO2(VI). Structures of the ligand and its metal complexes were identified by elemental analyses, IR, 1H and 13C NMR spectra and thermogravimetric analyses (TGA).
- Guengoer, O.,Canpolat, E.,Kaya, M.
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p. 403 - 410
(2007/10/03)
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- 2,4,4,6-Tetrabromo-2,5-cyclohexadienone (TABCO) as a versatile, efficient, and chemoselective catalyst for the acetalization and transacetalization of carbonyl compounds, the preparation of acetonides from epoxides and acylals (1,1-diacetates) from aldehydes
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The efficient and chemoselective preparation of acetals and ketals from carbonyl compounds, transacetalization reactions, the conversion of epoxides to acetonides, and the preparation of acylals from aldehydes in the presence of catalytic amounts of 2,4,4,6-tetrabromo-2,5-cyclohexadienone (TABCO) are described.
- Firouzabadi, Habib,Iranpoor, Nasser,Shaterian, Hamid Reza
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p. 2195 - 2205
(2007/10/03)
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- Synthesis and heck reactions of ethenyl- and (Z)-butadien-1-yl nonaflate obtained by the fragmentation of furan derivatives
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The nonaflation of lithium enolates or of silyl enol ethers, formally derived from acetaldehyde or crotonaldehyde, with nonafluorobutanesulfonyl fluoride gave ethenyl nonaflate (1b) and (Z)-buta-1,3-dien-1-yl nonaflate (2) in good yields. The required enolates were obtained by aldehyde-free routes by the lithiation of tetrahydrofuran or 2,5-dihydrofuran followed by the cyclofragmentation of the metallated heterocycles. The application of this approach to the synthesis of allenyl nonaflate 3 failed, presumably due to the intrinsic instability of this allene derivative. The nonaflates 1b and 2 were also prepared by the fluoride-catalysed reaction of the corresponding silyl enol ethers 5 and 7 with nonafluorobutanesulfonyl fluoride; however, the overall yields are slightly lower for these two-step pathways. The cyclofragmentation of lithiated 2,2-dimethyl-4-methylene-[1,3]dioxolane allowed the easy preparation of trimethylsiloxyallene (10) in moderate yield. The nonaflates 1b and 2 reacted smoothly with monosubstituted alkenes in the presence of a catalytic amount of palladium(II) acetate to give the anticipated Heck coupling products in good to moderate yields and with high stereoselectivities.
- Lyapkalo, Ilya M.,Webel, Matthias,Reissig, Hans-Ulrich
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p. 4189 - 4194
(2007/10/03)
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- Efficient conversion of epoxides to 1,3-dioxolanes catalyzed by bismuth(III) salts
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Epoxides react with acetone in the presence of catalytic amounts of bismuth(III) salts including BiCl3, Bi(TFA)3 and Bi(OTf)3 affording the corresponding 1,3-dioxolanes in excellent yields.
- Mohammadpoor-Baltork,Khosropour,Aliyan
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p. 3411 - 3416
(2007/10/03)
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- Conversion of epoxides into 1,3-dioxolanes catalysed by high oxidation state metalloporphyrins
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Tin(IV) tetraphenylporphyrin perchlorate, Sn(IV)(tpp)(ClO4)2, catalyses the efficient reaction of epoxides with acetone to give the corresponding 1,3-dioxolanes in good yields.
- Tangestaninejad,Habibi,Mirkhani,Moghadam
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p. 365 - 367
(2007/10/03)
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- Process for preparation of 1,3-dioxolane-4-methanol compounds
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PCT No. PCT/JP97/03165 Sec. 371 Date Feb. 8, 1999 Sec. 102(e) Date Feb. 8, 1999 PCT Filed Sep. 9, 1997 PCT Pub. No. WO98/11087 PCT Pub. Date Mar. 19, 1998A process for preparing easily and economically a 1,3-dioxolane-4-methanol compound in a racemic form or an optically active form with high purity and in high yield. The process comprises reacting an alkali metal or alkaline earth metal salt of an alcohol or a carboxylic acid with a halogenomethyl-1,3-dioxolane which is prepared by acetalizing a halogeno-1,2-propanediol of a formula (1) wherein X is a halogen atom, in an acid catalyst to conduct esterification or etherification, and then hydrolyzing the ester group and hydrogenolyzing the ether group to prepare a 1,3-dioxolane-4-methanol compound of a formula (5) wherein R1 and R2 are hydrogen atom, alkyl having 1 to 4 carbon atoms or phenyl, and R1 and R2 may form a cycloalkyl ring having 3 to 6 carbon atoms with the adjacent carbon atoms.
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- Iron(III) trifluoroacetate as an efficient catalyst for solvolytic and nonsolvolytic nucleophilic ring opening of epoxides
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Iron(III) trifluoroacetate was used as an efficient and nonhygroscopic catalyst for the alcoholysis, hydrolysis, and acetolysis of epoxides. The addition of chloride, bromide, iodide, and nitrate ions to epoxides to produce the corresponding 2-halo and 2-nitratoalkanols and also the conversion of epoxides to acetonides and thiiranes were also performed efficiently in the presence of this catalyst.
- Iranpoor, Nasser,Adibi, Hadi
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p. 675 - 680
(2007/10/03)
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- Ru(III) catalyses the conversion of epoxides to 1,3-dioxolanes
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Anhydrous RuCl3 catalyses the efficient reaction of epoxides with acetone to give the corresponding 1,3-dioxolanes in high yields.
- Iranpoor,Kazemi
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p. 3189 - 3193
(2007/10/03)
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- Cationic [99mTcIII(DIARS)2(SR)2]+ complexes as potential myocardial perfusion imaging agents (DIARS = o-phenylenebis(dimethylarsine);SR- = thiolate).
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Reduction-substitution reactions on [99mTcO4]- with both o-phenylenebis(dimethylarsine) (DIARS) and various thiols produce a series of monocationic [99Tc(DIARS)2(SR)2]+ complexes. Addition of [99gTcO4]- to the above reaction mixtures allows the characterization of the "carrier-added" complexes by means of reverse-phase high-performance liquid chromatography with radiometric and optical detection systems. The identity of the [99mTc(DIARS)2(SR)2]+ complexes is confirmed by fast atom bombardment mass spectroscopy; equivalence of the [99gTc(DIARS)2-(SR)2]+ and [99mTc(DIARS)2(SR)2]+ species is demonstrated by identical HPLC retention times. All the [99mTc(DIARS)2(SR)2]+ complexes tested accumulate in the myocardium of Sprague-Dawley rats with an average uptake of 1.5-2.0% of injected dose/g at 30 min. Thus, as designed, these nonreducible Tc(III) complexes do not exhibit the rapid myocardial washout observed for reducible Tc(III) complexes. These [99mTc(DIARS)2(SR)2]+ complexes also exhibit an initially high liver uptake, but the presence of ether groups within the thiolate ligands causes this liver uptake to decrease over time without affecting the heart uptake, thereby improving the heart/liver ratio.
- Tisato,Maina,Shao,Heeg,Deutsch
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p. 1253 - 1261
(2007/10/03)
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- Stereoselective Syntheses of Both Enantiomers of Ketoconazole from (R)- and (S)-Epichlorohydrin
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Stereoselective syntheses of both enantiomers of ketoconazole (1) from commercially available (R)- or (S)-epichlorohydrin has been developed.The key-step of syntheses involves the selective substitution of the methylene chlorine atom by benzoate on a mixture of (2S,4R)-14a and (2R,4R)-15a or of their enentiomers, followed by crystalization of the corresponding cis-benzoates, (2R,4R)-18 or (2S,4S)-18, from which (+)- or (-)-1 were obtained as described for (+/-)-1.The ee's of (+)- and (-)-ketocanazole were determined by HPLC on the CSP Chiracel OD-H.
- Camps, Pelayo,Farres, Xavier,Garcia, Luisa,Ginesta, Joan,Pascual, Jaume,et al.
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p. 1283 - 1294
(2007/10/03)
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- Synthesis and Hydrolysis of Chemodegradable Cationic Surfactants Containing the 1,3-Dioxolane Moiety
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In acid-catalyzed reactions of long-chain aliphatic aldehydes (Ia-d where a = n-C7H15; b = n-C9H19; c = n-C11H23; d = n-C13H27), and tridecan-7-on (Ie) with 3-chloro-1,2-propane-diol, 2-alkyl- and 2,2-dihexyl-4-chloromethyl-1,3-dioxolanes (IIa-e) were obtained.They were reacted with anhydrous dimethylamine to obtain, respectively, 2-alkyl- and dimethylamines (IIIa-e), which were quaternized with methyl bromide to obtain the desired ammonium bromides (IVa-e).The structure and purity of the compounds was proved by mass spectrometry and proton magnetic resonance spectroscopy.Additionally, trimethylammonium bromide and trimethylammonium bromide were synthesized as nonaggregating standards.Hydrolysis reactions of the synthesized ammonium bromides were performed by 0.1 M hydrochloric acid in 1:1 (vol/vol) 1,4-dioxane-water mixtures at 50, 60 and 70 deg C.Rate constants of hydrolysis reactions were determined by observing carbonyl group formation at 280 nm.The hydrolytic reactivity of the studied surfactants (IVa-c,e) was determined under unaggregated conditions.Compound IVd showed decreased reactivity.The length of the 2-alkyl group has a minor effect on rate constant values.The influence of various substituents at the C-4 atom of the 2-nonyl-1,3-dioxolan-4-yl derivatives on rate constants was also investigated. KKEY WORDS: trimethylammonium bromides, trimethylammonium bromide, chemodegradable acetal-type cationic surfactants, kinetic and thermodynamic parameters of 1,3-dioxolane ring hydrolysis.
- Wilk, Kazimiera A.,Bieniecki, Albert,Burczyk, Bogdan,Sokolowski, Adam
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- Novel esters of phenylalkanoic acid
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The esters of phenylalkanoic acid of the formula: STR1 wherein R 1 is 4-10 membered, saturated or unsaturated, mono- or bi-cyclic hetero ring containing as hetero atoms:(i) one or two nitrogen,(ii) two or three of nitrogen and sulfur in total, or(iii) one or two sulfur;R 2 is hydrogen; orR 1 and R 2, taken together with a nitrogen to which they are attached, form 4-7 membered, saturated or unsaturated, mono-cyclic hetero ring containing as hetero atoms:(i) one or two nitrogen, or(ii) two or three of nitrogen and oxygen in total,the aforementioned hetero rings, represented by R 1 or formed by R 1 and R 2, taken together with a nitrogen to which they are attached, may be substituted by one substituent selected from C1-4 alkyl and C2-5 acyl;R 3 each, independently, is hydrogen or C1-4 alkyl;R 4 is hydrogen, halogen, trihalomethyl, C1-4 alkyl, C1-4 alkoxy, C2-5 acyl, cyano, nitro or nitroxy;R 5 each, independently, is hydrogen, C1-4 alkyl or phenyl; or the two R 5 ''s, taken together with a carbon to which they are attached, form cyclopentane or cyclohexane;and the pharmaceutically acceptable acid addition salts thereof, have β 1 -adrenergic receptor blocking activity, and therefore, are useful for the prevention of and/or in the treatment of cardiovascular diseases such as angina pectoris, myocardial infarction, congestive heart failure, hypertension, arrhythmia, etc.
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- TETRAFLUOROBORIC ACID - A NEW CATALYST FOR THE SYNTHESIS OF 1,3-DIOXOLANES. PREPARATION OF HYDROXYACETONE
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It is established that tetrafluoroboric acid (HBF4) is an effective catalyst for halogen substitution reactions of oxiranes (epichlorohydrin and 1-bromo-3-methyl-2,3-epoxybutane) with aldehydes and ketones, forming 1,3-dioxolanes in high yield.
- Gevorkyan, A. A.,Kazaryan, P. I.,Avakyan, O. V.,Vardanyan, R. A.
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- N-Benzyl Pyridinium Salta as New Useful Catalysts for Transformation of Epoxides to Cyclic Acetals, Orthoesters, and Orthocarbonates
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In the presence of catalytic amount of N-(4-methoxybenzyl)-2-cyanopyridinium hexafluoroantimonate, the reaction of a few epoxides with aldehydes, ketones, lactones, and carbonates efficiently afforded corresponding cyclic acetals, orthoesters, and orthocarbonates under mild conditions.
- Lee, Sang-Bong,Takata, Toshikazu,Endo, Takeshi
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p. 2019 - 2022
(2007/10/02)
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- Oxime ethers, the preparation thereof, compositions containing them and use thereof
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The invention relates to oxime ethers of the formula I STR1 wherein n is 1 or 2, each of R1 and R2 is hydrogen or C1 -C4 alkyl each of R3 and R4 is hydrogen, halogen, C1 -C4 alkyl, C1 -C4 haloalkyl, C1 -C4 alkoxy, C1 -C4 haloalkoxy, C1 -C4 alkylthio, C1 -C4 haloalkylthio, C1 -C4 alkylsulfinyl, C1 -C4 alkylsulfonyl, C1 -C4 haloalkylsulfinyl, C1 -C4 haloalkylsulfonyl or nitro; each of R5 and R6 independently of the other is hydrogen, C1 -C4 alkyl, C1 -C4 haloalkyl, phenyl or phenyl which is substituted by halogen, C1 -C4 alkyl, C1 -C4 haloalkyl, C1 -C4 alkoxy, C1 -C4 haloalkoxy, C1 -C4 alkylthio, C1 -C4 alkylsulfinyl, C1 -C4 alkylsulfonyl, carboxyl, carbamoyl, C 1 -C4 alkylcarbamoyl, nitro or cyano, or R5 and R6 together are also a 2- to 6-membered alkylene or alkenylene chain which may be substituted by C1 -C4 alkyl radicals; X is hydrogen, cyano, nitro, chlorine, C1 -C4 alkyl, C1 -C4 haloalkyl, C3 -C6 cycloalkyl, carboxyl, carbamoyl, C1 -C4 alkylcarbonyl, C1 -C4 alkoxycarbonyl or C1 -C4 alkylcarbamoyl. The oxime ethers of the formula I are able to act as antidotes or safeners to protect cultivated plants from the phytotoxic effects of herbicides. Such cultivated plants are preferably sorghum, cereals, maize and rice.
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- PERFLUORINATED RESINSULFONIC ACID - A CATALYST FOR CERTAIN ORGANIC REACTIONS.
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The purpose of this work was to examine the possibility of using, as a catalyst in certain organic reactions, the perfluorinated resinsulfonic acid F-4SK in the H form, which is an analog of the perfluorinated resinsulfonic acid Nafion-H. To compare catalyst activity of the perfluorinated resinsulfonic acid in decomposition of cumene hydroperoxide, CHP was also decomposed in presence of KU-2 resin. It was found that during repeated use over a period of 150 h the activity of KU-2 catalyst under analogous conditions fell by 4-6%. During the same time the activity of the perfluorinated resinsulfonic acid remained unchanged. It is also known that the presence of a strong acid in the reaction mixture causes formation of by-products, namely the products of condensation of phenol with acetone and dimethylphenylcarbinol, and of dehydration of dimethylphenylcarbinol, with formation of alpha -methylstyrene and products of greater complexity.
- Etlis,Beshenova,Semenova,Shomina,Dreiman,Balaev
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p. 551 - 555
(2007/10/02)
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- ANALYTICAL ENANTIOMER SEPARATION OF ALIPHATIC DIOLS AS BORONATES AND ACETALS BY COMPLEXATION GAS CHROMATOGRAPHY
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Cyclic boronates and acetals of mono- and dialkylsubstituted 1,2-, 2,3- 1,3-and 1,4-diols have been quantitatively separated into enantiomers by complexation gas chromatography utilizing optically active metal chelates.An efficient, precise and sensitive method for determining enantiomeric purities for volatile glycols is thus available.
- Schurig, V.,Wistuba, D.
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p. 5633 - 5636
(2007/10/02)
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- Preparation of Alkyl Chlorides, Acid Chlorides, and Amides Using Polymer-Supported Phosphines and Carbon Tetrachloride: Mechanism of These Reactions
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Alcohols and thiols were converted into alkyl chlorides, carboxylic acids were converted into acid chlorides, and mixtures of carboxylic acids and amines were converted into amides by reaction with carbon tetrachloride and 1percent cross-linked polystyrenes containing phosphine residues.Some of these conversions were also effected by using a linear polymer containing phosphine residues.The reactions proceed in high yield, and isolation of the products is facilitated by the ready removal of all the polymer-supported species.The mechanism of the reactions between triphenylphosphine, carbon tetrachloride, and alcohols is complex, but the polymer-supported reactions appear to follow analogous pathways to the low molecular weight reactions as judged by the yields of chloroform and the number of equivalents of phosphine consumed per mole of alkyl chloride produced.The mechanism requires polymer-supported groups reacting together.The slow step in the reactions appears to be the generation of the chlorinating species.The polymer-supported reactions are faster than those using triphenylphosphine or 4-(diphenylphosphinyl)isopropylbenzene.It is suggested that this is due to a microenvironmental effect.
- Harrison, Charles R.,Hodge, Philip,Hunt, Barry J.,Khoshdel, Ezzatollah,Richardson, Graham
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p. 3721 - 3728
(2007/10/02)
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- FORMATION DE DIOXOLANNES A PARTIR DE L'EPICHLORHYDRINE DU GLYCEROL. HYDROLYSE AISEE DE DIOXOLANNES PAR LE TOSYLATE DE PYRIDINIUM
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We described a versatile synthesis of dioxolanne from 1-chlor 2,3-epoxypropane epichlorhydrine and different carbonyl compounds in presence of activated montmorillonite which is easily eliminated after the reaction.The hydrolysis was performed in mild conditions with pyridinium p-toluene sulfonate.
- Thuy, Vu Moc,Petit, Huguette,Maitte, Pierre
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p. 759 - 762
(2007/10/02)
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