cas 4410-12-2, 1-BENZYL-1,4-DIAZEPANE | Articles data ｜lookchem

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4410-12-2

Articles about 4410-12-2Total 3 be found

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DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS
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Page/Page column 81-82

(2010/11/30)

DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS
Cyclic diamines of formula (I) or their pharmacologically acceptable acid addition salts, and their medical applications are described. These compounds inhibit the action of chemokines such as MIP-la and/or MCP-l on target cells, and are useful as a therapeutic drug and/or preventative drug in diseases, such as atherosclerosis, rheumatoid arthritis, and the like where blood monocytes and lymphocytes infiltrate into tissues.
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(2008/06/13)

Saturated heterocyclic carboxamide derivatives
A saturated heterocyclic carboxamide derivative of the following general formula (I) and salts thereof which have platelet activating factor (PAF) antagonizing activity. STR1
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(2008/06/13)

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Chemical Properties

Appearance/Colour :colorless liquid.
Melting Point: 54-56 °C
Boiling Point: 286.465 °C at 760 mmHg
Flash Point:116.22 °C
Density: 1.004 g/cm³
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
Vapor Pressure: 0.00263mmHg at 25°C
Refractive Index: n20/D 1.547
PKA: 10.59±0.20(Predicted)
Sensitive: Air Sensitive
BRN: 147009
PSA: 15.27000
LogP: 1.74860

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