A microwave assisted intramolecular-furan-Diels-Alder approach to 4-substituted indoles
The key steps of a versatile new protocol for the convergent synthesis of 3,4-disubstituted indoles are the addition of an α-lithiated alkylaminofuran to a carbonyl compound, a microwave-accelerated intramolecular Diels-Alder cycloaddition and an in situ
Petronijevic, Filip,Timmons, Cody,Cuzzupe, Anthony,Wipf, Peter
supporting information; experimental part
p. 104 - 106
(2009/03/11)
4-aryl substituted indolinones
The present invention relates to 4-arylindolinones, as well as pharmaceutical compositions thereof, capable of modulating protein kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation. The present invention also relates to methods for treating protein kinase related disorders.
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(2008/06/13)
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