5-amino-2-furylmethylamines - Appealing precursors of amino-isoindolinones?
Isoindolinones were constructed according to an original [4+2]-cycloaddition strategy. Unprecedented 5-amino-2-furyl-methylamines were prepared and revealed as efficient precursors of new aminoisoindolinones, obtained via a Diels-Alder and lactamization sequence. Georg Thieme Verlag Stuttgart · New York.