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453562-69-1

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SUBSTITUTED ALKYLAMINE DERIVATIVES AND METHODS OF USE
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(2008/06/13)

Substituted alkylamine derivatives and methods of use
Selected heterocyclic compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
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(2008/06/13)

Substituted alkylamine derivatives and methods of use
Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
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Page 126

(2010/02/05)

More Articles about upstream products of 453562-69-1

453562-74-8
N-(1-acetyl-3,3-dimethylindolin-6-yl){2-[(4-pyridylmethyl)-amino](3-pyridyl)}-carboxamide

More Articles about downstream products of 453562-69-1

1376615-70-1
3,3-dimethyl-N-((2-(pyridin-4-ylmethylamino)pyridin-3-yl)methyl)indolin-6-amine

Chemical Properties

Boiling Point: 517.258 °C at 760 mmHg
Flash Point:266.628 °C
Density: 1.251 g/cm³
Solubility:DMSO (Slightly), Methanol (Slightly)
Storage Temp.:Refrigerator
Vapor Pressure: 0mmHg at 25°C
Refractive Index: 1.669
PKA: 11.75±0.40(Predicted)
PSA: 78.94000
LogP: 4.32810

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