- Enantioselective Synthesis of 2-Functionalized Tetrahydroquinolines through Biomimetic Reduction
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Biomimetic asymmetric reduction of 2-functionalized quinolines has been successfully developed with the chiral and regenerable NAD(P)H model CYNAM in the presence of transfer catalyst simple achiral phosphoric acids, providing the chiral 2-functionalized
- Zhao, Zi-Biao,Wang, Jie,Zhu, Zhou-Hao,Chen, Mu-Wang,Zhou, Yong-Gui
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supporting information
p. 9112 - 9117
(2021/11/24)
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- ANTAGONISTS OF THE TRPV1 RECEPTOR AND USES THEREOF
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The present application is directed to compounds that are TRPV1 antagonists and have formula (I) wherein variables Ar1, L1, R1, R2, R3, R4, R5, Y1, Y2, and Y3, are as defined in the description, which are useful for treating disorders caused by or exacerbated by vanilloid receptor activity.
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Page/Page column 32
(2008/12/06)
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- 7-fused 2-(piperazinoalkyl) indole derivatives, intermediates and compositions thereof
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Pharmacologically active compounds having anti-allergic properties corresponding to the formula I STR1 which can be mono- or disubstituted in the phenyl ring and their acid addition salts and/or S-mono- or dioxides of sulfur-containing compounds of the formula I are described, together with processes and intermediates for their preparation.
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- Reduction of Quinolinecarboxylic Acids by Raney Alloy
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The heterocyclic nucleus in quinolinecarboxylic acids is reduced by Raney alloy (nickel-aluminium) in alkaline media to give 1,2,3,4-tetrahydro-2-,3-,4-,5-,6-, and 8-quinolinecarboxylic acids and 8-methyl-5-quinolinecarboxylic acid and their ethyl esters.
- Gracheva, I. N.,Tochilkin, A. I.
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