PHOTOLABILE COMPOUND, OLIGOMER PROBE ARRAY AND SUBSTRATE FOR OLIGOMER PROBE ARRAY CONTAINING THE SAME, AND MANUFACTURING METHOD OF THE SAME
A photolabile compound, an oligomer probe array, and a substrate for oligomer probe array comprising the same, and a manufacturing method of the same are disclosed.
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(2008/12/07)
Photolabile Compound and Substrate for Oligomer Probe Array with the Same
Provided is a substrate for an oligomer probe array to which a photolabile material having an acetylene derivative is directly attached or attached via a linker.
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(2008/06/13)
Method of treating cancer using FPT inhibitors and antineoplastic agents
Disclosed is a method of treating cancer in a patient in need of such treatment comprising administering a therapeutically effective amount of an FPT inhibitor and therapeutically effective amounts of one or more antineoplastic agents. Methods of treating non small cell lung cancer, squamous cell cancer of the head and neck, CML, AML, non-Hodgkin's lymphoma and multiple myeloma are disclosed.
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(2008/06/13)
Novel farnesyl protein transferase inhibitors as antitumor agents
The present invention discloses novel tricyclic compounds represented by the formula (1.0): a prodrug thereof, or a pharmaceutically acceptable salt or solvate of the compound or of said prodrug useful for inhibiting farnesyl protein transferase. Also disclosed are pharmaceutical compositions comprising such compounds their preparation as well as methods of using them to treat proliferative diseases such as cancer.
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(2008/06/13)
3-Unsubstituted-3-cephem compounds
Antibacterial compounds represented by the following formula including their pharmaceutically acceptable salts and esters; process for preparing them; pharmaceutical preparation comprising them; and method for combating infections by administering them: S